# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3773708 | Binding | Inhibition of recombinant HIs-tagged human GAC (residue 72-603 aa) expressed in Escherichia coli after 10 mins using glutamine as substrate | Homo sapiens | 33 | ALA3769321 | assay format | Scientific Literature | |
2. | ALA3773709 | Functional | Cytotoxicity against human MDA-MB-231 cells measured on 6th day by hemocytometry | Homo sapiens | 33 | ALA3769321 | cell-based format | Scientific Literature | |
3. | ALA4360333 | Binding | Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by amplex red staining-based horseradish peroxidase/glutamate oxidase coupled assay | Homo sapiens | 26 | ALA4359817 | assay format | Scientific Literature | |
4. | ALA4360334 | Binding | Inhibition of GLS2 (unknown origin) | Homo sapiens | 16 | ALA4359817 | single protein format | Scientific Literature | |
5. | ALA4360335 | Binding | Inhibition of GLS in human PC3 cells using glutamine as substrate measured after 6 hrs by amplex red staining-based horseradish peroxidase/glutamate oxidase coupled assay | Homo sapiens | 26 | ALA4359817 | cell-based format | Scientific Literature | |
6. | ALA4360337 | Physicochemical | Thermodynamic aqueous solubility of the compound at pH 7.4 | 21 | ALA4359817 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA4360338 | Physicochemical | Lipophilicity, log D of the compound at pH 7.4 | 22 | ALA4359817 | small-molecule physicochemical format | Scientific Literature |