| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3773182 | F | Induction of apoptosis in Bax deficient human HCT116 cells assessed as late apoptotic cells at 15 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 1.5 to 1.56%) | Homo sapiens | 1 | ALA3769391 | cell-based format | Scientific Literature | |
| 2. | ALA3773183 | F | Induction of apoptosis in Bax deficient human HCT116 cells assessed as early apoptotic cells at 15 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 0.85 to 1.13%) | Homo sapiens | 1 | ALA3769391 | cell-based format | Scientific Literature | |
| 3. | ALA3773184 | F | Induction of apoptosis in human HCT116 cells assessed as cytochrome C release from mitochondria to cytoplasm at 5 uM after 12 hrs by immunofluorescence assay | Homo sapiens | 1 | ALA3769391 | mitochondrion format | Scientific Literature | |
| 4. | ALA3773185 | F | Induction of apoptosis in human HCT116 cells assessed as viable cells at 5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 93.64%) | Homo sapiens | 1 | ALA3769391 | cell-based format | Scientific Literature | |
| 5. | ALA3773341 | T | Hepatotoxicity in immune deficient nude BALB/c mouse xenografted with Bax deficient human HCT116 cells assessed as changes in alanine transaminase level in serum at 5 and 10 mg/kg, ip administered every other day for 2 weeks measured during compound dosing | Mus musculus | 1 | ALA3769391 | organism-based format | Scientific Literature | |
| 6. | ALA3773342 | F | Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 1 | ALA3769391 | cell-based format | Scientific Literature | |
| 7. | ALA3773343 | F | Induction of apoptosis in human HCT116 cells assessed as early apoptotic cells at 2.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 1.06%) | Homo sapiens | 1 | ALA3769391 | cell-based format | Scientific Literature | |
| 8. | ALA3773344 | F | Induction of apoptosis in human HCT116 cells assessed as late apoptotic cells at 2.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 4.54%) | Homo sapiens | 1 | ALA3769391 | cell-based format | Scientific Literature | |
| 9. | ALA3773345 | F | Induction of apoptosis in human HCT116 cells assessed as early apoptotic cells at 5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 1.06 to 2.2%) | Homo sapiens | 1 | ALA3769391 | cell-based format | Scientific Literature | |
| 10. | ALA3773346 | F | Induction of apoptosis in human HCT116 cells assessed as late apoptotic cells at 5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 3.73 to 4.54%) | Homo sapiens | 1 | ALA3769391 | cell-based format | Scientific Literature | |
| 11. | ALA3773347 | F | Induction of apoptosis in human HCT116 cells assessed as early apoptotic cells at 7.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 1.06%) | Homo sapiens | 1 | ALA3769391 | cell-based format | Scientific Literature | |
| 12. | ALA3773348 | F | Induction of apoptosis in human HCT116 cells assessed as late apoptotic cells at 7.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 4.54%) | Homo sapiens | 1 | ALA3769391 | cell-based format | Scientific Literature | |
| 13. | ALA3773349 | F | Induction of apoptosis in human HCT116 cells assessed as early apoptotic cells at 10 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 1.06%) | Homo sapiens | 1 | ALA3769391 | cell-based format | Scientific Literature | |
| 14. | ALA3773350 | F | Induction of apoptosis in human HCT116 cells assessed as late apoptotic cells at 10 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 4.54%) | Homo sapiens | 1 | ALA3769391 | cell-based format | Scientific Literature | |
| 15. | ALA3773351 | F | Induction of apoptosis in human HCT116 cells assessed as early apoptotic cells at 10 uM after 12 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 1.13%) | Homo sapiens | 2 | ALA3769391 | cell-based format | Scientific Literature | |
| 16. | ALA3773352 | F | Induction of apoptosis in human HCT116 cells assessed as late apoptotic cells at 10 uM after 12 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 3.37%) | Homo sapiens | 2 | ALA3769391 | cell-based format | Scientific Literature | |
| 17. | ALA3773353 | F | Induction of apoptosis in human HCT116 cells by Annexin V-FITC/propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA3769391 | cell-based format | Scientific Literature | |
| 18. | ALA3773354 | F | Induction of apoptosis in human SW480 cells assessed as apoptotic cells at 10 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA3769391 | cell-based format | Scientific Literature | |
| 19. | ALA3773355 | F | Induction of apoptosis in human HCT116 cells assessed as caspase activation at 5 uM after 12 hrs by CaspACEFITC-VAD-FMK staining based flow cytometry (Rvb = 7.72%) | Homo sapiens | 1 | ALA3769391 | cell-based format | Scientific Literature | |
| 20. | ALA3773356 | F | Induction of apoptosis in human HCT116 cells assessed as caspase activation at 5 uM after 24 hrs by CaspACEFITC-VAD-FMK staining based flow cytometry (Rvb = 7.72%) | Homo sapiens | 1 | ALA3769391 | cell-based format | Scientific Literature |
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