# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3773193 | F | Selectivity index, ratio of EC50 for Dengue virus to EC50 for HCV | 2 | ALA3769315 | assay format | Scientific Literature | ||
2. | ALA3773195 | F | Antiviral activity against HCV JFH-1 infected in Huh7.5.1 cells after 48 hrs by luciferase reporter gene assay | Hepacivirus hominis | 51 | ALA3769315 | organism-based format | Scientific Literature | |
3. | ALA3773196 | A | Cytotoxicity against human Huh7.5.1 cells assessed as ATP level by luminescence analysis | Homo sapiens | 51 | ALA3769315 | cell-based format | Scientific Literature | |
4. | ALA3773197 | T | Selectivity index, ratio of CC50 for human Huh7.5.1 cells infected with HCV JFH-1 virus to EC50 for HCV JFH-1 virus | 51 | ALA3769315 | cell-based format | Scientific Literature | ||
5. | ALA3773199 | A | Cytotoxicity against human HepG2 cells assessed as ATP level by luminescence analysis | Homo sapiens | 8 | ALA3769315 | cell-based format | Scientific Literature | |
6. | ALA3774135 | A | Cytotoxicity against human primary hepatocytes assessed as ATP level by luminescence analysis | Homo sapiens | 9 | ALA3769315 | cell-based format | Scientific Literature | |
7. | ALA3774136 | A | Inhibition of histamine H1 receptor (unknown origin) assessed as inhibition of histamine-induced beta-arrestin internalization preincubated at 10 nM for 3 hrs followed by addition of 0.25 uM histamine measured after 2 hrs by PathHunter cell based assay | Homo sapiens | 10 | ALA3769315 | cell-based format | Scientific Literature | |
8. | ALA3774137 | F | Antiviral activity against single rounded infectious HCV infected in human Huh7.5.1 cells assessed as viral level at 10 uM after 48 hrs by luciferase reporter gene assay | Hepacivirus hominis | 9 | ALA3769315 | organism-based format | Scientific Literature | |
9. | ALA3774145 | A | Permeability of compound by PAMPA method | 6 | ALA3769315 | assay format | Scientific Literature | ||
10. | ALA3774146 | P | Solubility of compound in phosphate buffer at pH 7.4 | 9 | ALA3769315 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA3774172 | F | Antiviral activity against Hepatitis B virus | Hepatitis B virus | 1 | ALA3769315 | organism-based format | Scientific Literature | |
12. | ALA3774173 | F | Selectivity index, ratio of EC50 for Hepatitis B virus to EC50 for HCV | 1 | ALA3769315 | assay format | Scientific Literature | ||
13. | ALA3774174 | F | Antiviral activity against HCV replicon | Hepacivirus hominis | 1 | ALA3769315 | organism-based format | Scientific Literature | |
14. | ALA3774175 | F | Selectivity index, ratio of EC50 for HCV replicon to EC50 for HCV | 1 | ALA3769315 | assay format | Scientific Literature | ||
15. | ALA3771411 | F | Antiviral activity against Herpes simplex virus-1 | Human alphaherpesvirus 1 | 1 | ALA3769315 | organism-based format | Scientific Literature | |
16. | ALA3771412 | F | Selectivity index, ratio of EC50 for Herpes simplex virus to EC50 for HCV | 1 | ALA3769315 | assay format | Scientific Literature | ||
17. | ALA3771413 | F | Antiviral activity against human cytomegalovirus | Human betaherpesvirus 5 | 1 | ALA3769315 | organism-based format | Scientific Literature | |
18. | ALA3771414 | F | Selectivity index, ratio of EC50 for human cytomegalovirus to EC50 for HCV | 1 | ALA3769315 | assay format | Scientific Literature | ||
19. | ALA3771415 | F | Antiviral activity against vaccinia virus | Vaccinia virus | 1 | ALA3769315 | organism-based format | Scientific Literature | |
20. | ALA3771416 | F | Selectivity index, ratio of EC50 for vaccinia virus to EC50 for HCV | 1 | ALA3769315 | assay format | Scientific Literature |