| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3772327 | B | Binding affinity to recombinant N-terminal GST-tagged HIV1 NL4-3 capsid C-terminal domain (146 to 231 residues) incubated for 2 hrs by alphascreen assay | Human immunodeficiency virus 1 | 26 | assay format | Scientific Literature | ||
| 2. | ALA3772328 | F | Antiviral activity against HIV1 NL4-3 infected in human TZM-bl cells assessed as inhibition of viral replication administered 6 hrs postinfection measured 48 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 25 | organism-based format | Scientific Literature | ||
| 3. | ALA3772329 | A | Cytotoxicity against human TZM-bl cells assessed as cell viability at 10 uM after 48 hrs by MTS assay relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 4. | ALA4015695 | B | Inhibition of recombinant human GFP-fused ABCG2 expressed in MDCK2 cells assessed as reduction in Hoechst 33342 efflux preincubated for 30 mins followed by Hoechst 33342 addition measured immediately at 60 sec time interval for 120 mins by fluorescence assay | Homo sapiens | 44 | cell-based format | Scientific Literature | ||
| 5. | ALA4015696 | B | Inhibition of recombinant human GFP-fused ABCG2 expressed in MDCK2 cells assessed as reduction in Hoechst 33342 efflux at 10 mM preincubated for 30 mins followed by Hoechst 33342 addition measured immediately at 60 sec time interval for 120 mins by fluorescence assay relative to Ko143 | Homo sapiens | 44 | cell-based format | Scientific Literature | ||
| 6. | ALA4015697 | B | Inhibition of ABCB1 in human A2780adr cells assessed as reduction in calcein AM levels preincubated for 30 mins followed by calcein AM addition measured immediately at 60 sec time interval for 60 mins by fluorescence assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 7. | ALA4015698 | B | Inhibition of ABCB1 in human A2780adr cells assessed as reduction in calcein AM levels at 10 uM preincubated for 30 mins followed by calcein AM addition measured immediately at 60 sec time interval for 60 mins by fluorescence assay relative to Cyclosporine A | Homo sapiens | 10 | cell-based format | Scientific Literature |
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