| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3779163 | B | Binding affinity to human EGFP-tagged SOD1 A4V mutant mRNA expressed in mouse Neuro2a cells assessed as reduction in cells bearing inclusions at 25 uM measured 72 hrs post transfection by Hoechst33342 staining-based epifluorescence microscopic analysis (Rvb = 19 to 21%) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 2. | ALA3779164 | B | Inhibition of human EGFP-tagged SOD1 A4V mRNA mutant induced endoplasmic reticulum stress expressed in mouse Neuro2a cells assessed as reduction in nuclear CHOP activation at 25 uM measured 72 hrs post transfection by Hoechst33342 staining-based epifluorescence microscopic analysis (Rvb = 35 to 37%) | Homo sapiens | 7 | cell-based format | Scientific Literature |
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