# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3776607 | B | Displacement of [3H]-spiperone from human dopamine D3 receptor expressed in CHO-K1 cell membranes after 90 mins by liquid scintillation counter method | Homo sapiens | 65 | cell-based format | Scientific Literature | ||
2. | ALA3776608 | B | Displacement of [3H]-spiperone from human dopamine D2 receptor expressed in CHO-K1 cell membranes after 120 mins by liquid scintillation counter method | Homo sapiens | 65 | cell-based format | Scientific Literature | ||
3. | ALA3776609 | B | Inhibition of human ERG tail current expressed in HEK293 cells after 5 mins by patch clamp assay | Homo sapiens | 65 | cell-based format | Scientific Literature | ||
4. | ALA3776862 | A | Intrinsic clearance in rat liver microsomes assessed per mg of protein at 0.5 uM preincubated for 30 mins followed by NADPH addition measured after 3 to 30 mins by HPLC-MS/MS analysis | Rattus norvegicus | 12 | tissue-based format | Scientific Literature | ||
5. | ALA3776863 | A | Intrinsic clearance in human liver microsomes assessed per mg of protein at 0.5 uM preincubated for 30 mins followed by NADPH addition measured after 3 to 30 mins by HPLC-MS/MS analysis | Homo sapiens | 12 | tissue-based format | Scientific Literature | ||
6. | ALA3776877 | A | Inhibition of recombinant human CYP3A4 expressed in baculosomes preincubated for 10 mins followed by cofactor addition measured every minute for 10 mins by CYPEX assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
7. | ALA3776879 | B | Selectivity ratio of Ki for human dopamine D2 receptor to Ki for human dopamine D3 receptor | Homo sapiens | 10 | assay format | Scientific Literature |