#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3777120	Binding	Inhibition of recombinant GGDPS (unknown origin) assessed as radiolabeled GGPP formation preincubated for 10 mins followed by addition of 10 uM FPP substrate and [14C]IPP for 30 mins by liquid scintillation counter analysis	Homo sapiens	4	ALA3774363	single protein format	Scientific Literature
2.	ALA3777121	Binding	Inhibition of recombinant FDPS (unknown origin) assessed as radiolabeled FPP formation preincubated for 10 mins followed by addition of 10 uM GPP substrate and [14C]IPP for 30 mins by liquid scintillation counter analysis	Homo sapiens	3	ALA3774363	single protein format	Scientific Literature
3.	ALA3777122	Binding	Selectivity index, ratio of IC50 for FDPS (unknown origin) to IC50 for GGDPS (unknown origin)	Homo sapiens	3	ALA3774363	assay format	Scientific Literature
4.	ALA3777123	Binding	Inhibition of GGDPS in human RPMI8226 cells assessed as disruption of Rap1a geranylation after 48 hrs by immunoblot analysis	Homo sapiens	3	ALA3774363	cell-based format	Scientific Literature
5.	ALA3777124	Binding	Inhibition of GGDPS in human RPMI8226 cells assessed as disruption of Rap1a geranylation at 50 nM after 48 hrs by ELISA	Homo sapiens	1	ALA3774363	cell-based format	Scientific Literature
6.	ALA3777125	Functional	Cytotoxicity against human RPMI8226 after 48 hrs by MTT assay	Homo sapiens	3	ALA3774363	assay format	Scientific Literature
7.	ALA4012294	Binding	Inhibition of recombinant GGDPS (unknown origin) using FPP as substrate pretreated for 10 mins followed by substrate addition after 30 mins in presence of [14C]-IPP by liquid scintillation counting analysis	Homo sapiens	4	ALA4011604	single protein format	Scientific Literature
8.	ALA4012304	Binding	Inhibition of GGTase1 in human RPMI8226 cells assessed as decrease in Rap1a geranylgeranylation after 48 hrs by Western blot method	Homo sapiens	1	ALA4011604	cell-based format	Scientific Literature
9.	ALA4012305	Binding	Inhibition of Rab GGTase2 in human RPMI8226 cells assessed as decrease in Rab GTPase geranylgeranylation by measuring accumulation of intracellular lambda light chain after 48 hrs by ELISA	Homo sapiens	1	ALA4011604	cell-based format	Scientific Literature
10.	ALA4012306	Binding	Inhibition of Rab GGTase2 in human RPMI8226 cells assessed as decrease in Rab6 geranylgeranylation after 48 hrs by western blot analysis	Homo sapiens	1	ALA4011604	cell-based format	Scientific Literature
11.	ALA4182960	Binding	Inhibition of recombinant GGDPS (unknown origin) using FPP as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins in presence of [14C]-IPP by liquid scintillation counting method	Homo sapiens	8	ALA4177743	single protein format	Scientific Literature