| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3778805 | Binding | Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for 10 mins measured after 20 mins by alphascreen assay | Homo sapiens | 56 | ALA3774338 | assay format | Scientific Literature | |
| 2. | ALA3778806 | Binding | Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as substrate preincubated for 10 mins measured after 20 mins by alphascreen assay | Homo sapiens | 56 | ALA3774338 | cell-based format | Scientific Literature | |
| 3. | ALA3778807 | Binding | Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by alphascreen assay | Homo sapiens | 56 | ALA3774338 | single protein format | Scientific Literature | |
| 4. | ALA3778979 | Binding | Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by alphascreen assay | Homo sapiens | 54 | ALA3774338 | single protein format | Scientific Literature | |
| 5. | ALA3776213 | ADME | Apparent permeability from apical to basolateral side in human Caco2 cells at 10 uM after 2 hrs by LC-MS/MS analysis | Homo sapiens | 26 | ALA3774338 | cell-based format | Scientific Literature |
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