# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3777946 | B | Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux at 50 uM incubated for 20 mins measured for 5 mins by real-time fluorometric analysis | Staphylococcus aureus | 48 | ALA3774342 | single protein format | Scientific Literature | |
2. | ALA3777947 | F | Antimicrobial activity against Staphylococcus aureus 1199B by microdilution method | Staphylococcus aureus | 48 | ALA3774342 | organism-based format | Scientific Literature | |
3. | ALA3777951 | A | Drug level in human liver microsomes treated with Ethyl 1-benzyl-2-methyl-5-(3-(piperidin-1-yl)propoxy)-1H-indole-3-carboxylate at 10 uM preincubated for 5 mins followed by NADPH addition measured after 30 mins by HPLC-MS/MS analysis | Homo sapiens | 2 | ALA3774342 | tissue-based format | Scientific Literature | |
4. | ALA3777955 | A | Drug level in human liver microsomes treated with Ethyl 1-(2-Methoxybenzyl)-2-methyl-5-(3-(piperidin-1-yl)-propoxy)-1H-indole-3-carboxylate at 10 uM preincubated for 5 mins followed by NADPH addition measured after 30 mins by HPLC-MS/MS analysis | Homo sapiens | 2 | ALA3774342 | tissue-based format | Scientific Literature | |
5. | ALA3778151 | B | Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-time fluorometric analysis | Staphylococcus aureus | 48 | ALA3774342 | single protein format | Scientific Literature |