# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3777946 | B | Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux at 50 uM incubated for 20 mins measured for 5 mins by real-time fluorometric analysis | Staphylococcus aureus | 48 | ALA3774342 | single protein format | Scientific Literature | |
2. | ALA3777947 | F | Antimicrobial activity against Staphylococcus aureus 1199B by microdilution method | Staphylococcus aureus | 48 | ALA3774342 | organism-based format | Scientific Literature | |
3. | ALA3778147 | A | Metabolic stability in human liver microsomes assessed as compound remaining after at 10 uM preincubated for 5 mins followed by NADPH addition measured after 30 mins by HPLC-MS/MS analysis | Homo sapiens | 8 | ALA3774342 | tissue-based format | Scientific Literature | |
4. | ALA3778151 | B | Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-time fluorometric analysis | Staphylococcus aureus | 48 | ALA3774342 | single protein format | Scientific Literature | |
5. | ALA3778162 | P | Solubility of the compound in D2O solution at 25 degC by 1H NMR analysis | 8 | ALA3774342 | small-molecule physicochemical format | Scientific Literature |