| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3778163 | B | Inhibition of human KDM6B catalytic domain using H3(20 to 36 residues)K27Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analysis | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 2. | ALA3778164 | B | Inhibition of KDM4C (unknown origin) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analysis | Homo sapiens | 34 | single protein format | Scientific Literature | ||
| 3. | ALA3778165 | B | Inhibition of human KDM4D (11 to 341 residues) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analysis | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 4. | ALA3778166 | B | Inhibition of full length His-MBP-att-EGLN3 (1 to 239 residues) (unknown origin) in Escherichia coli BL21(DE3)pRR692 cells assessed as hydroxylation of the cy-5 labelled C-terminal oxygen dependent domain of substrate Hif2A preincubated for 30 mins followed by substrate addition measured after 40 mins by TR-FRET assay | Homo sapiens | 10 | assay format | Scientific Literature | ||
| 5. | ALA3778169 | B | Inhibition of KDM4A (unknown origin) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 6. | ALA3778170 | B | Inhibition of KDM4E (unknown origin) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 7. | ALA3779254 | B | Inhibition of full length human HALO-tagged KDM4C expressed in human U2OS cells assessed as level of H3K9Me3 demethylation incubated overnight by Hoechst 33342/HaloTag/ Alexa Fluor 647 staining-based image analysis | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 8. | ALA3779256 | B | Inhibition of full length human HALO-tagged KDM5C1 expressed in human U2OS cells assessed as level of H3K9Me3 demethylation incubated overnight by Hoechst 33342/HaloTag/ Alexa Fluor 647 staining-based image analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA3779257 | B | Inhibition of KDM5C catalytic domain (1 to 764 residues) (unknown origin) expressed in Baculovirus-infected insect Sf9 cells using H3K4Me3 peptide as substrate assessed as demethylation of substrate preincubated for 10 mins followed by substrate addition in presence of alpha-ketoglutarate by Rapidfire mass spectrometric analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA3779258 | B | Inhibition of OATP1B1 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 11. | ALA5141139 | B | Inhibition of KDM4C (unknown origin) measured by RapidFire mass spectrometry (RFMS) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 12. | ALA5141140 | B | Inhibition of KDM4D (unknown origin) measured by RapidFire mass spectrometry (RFMS) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 13. | ALA5141141 | B | Inhibition of KDM5C (unknown origin) measured by RapidFire mass spectrometry (RFMS) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA5141201 | P | Lipophilicity, logD of compound at pH 7.4 by Chromatography | 2 | small-molecule physicochemical format | Scientific Literature |
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