# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3777271 | ADME | Mutagenicity in Vibrio harveyi BB7 assessed as number of colonies after 48 hrs (Rvb = 13 to 14 no_unit) | Vibrio harveyi | 11 | ALA3774372 | organism-based format | Scientific Literature | |
2. | ALA3777272 | ADME | Mutagenicity in Vibrio harveyi BB7X assessed as number of colonies after 48 hrs (Rvb = 15 to 16 no_unit) | Vibrio harveyi | 11 | ALA3774372 | organism-based format | Scientific Literature | |
3. | ALA3777273 | ADME | Mutagenicity in Vibrio harveyi BB7M assessed as number of colonies after 48 hrs (Rvb = 13 to 14 no_unit) | Vibrio harveyi | 11 | ALA3774372 | organism-based format | Scientific Literature | |
4. | ALA3777274 | ADME | Mutagenicity in Vibrio harveyi BB7XM assessed as number of colonies after 48 hrs (Rvb = 14 no_unit) | Vibrio harveyi | 11 | ALA3774372 | organism-based format | Scientific Literature | |
5. | ALA3777279 | Functional | Antimutagenic activity against Vibrio harveyi BB7 assessed as inhibition of NQNO-induced mutagenicity after 48 hrs | Vibrio harveyi | 9 | ALA3774372 | organism-based format | Scientific Literature | |
6. | ALA3777280 | Functional | Antimutagenic activity against Vibrio harveyi BB7X assessed as inhibition of NQNO-induced mutagenicity after 48 hrs | Vibrio harveyi | 8 | ALA3774372 | organism-based format | Scientific Literature | |
7. | ALA3777281 | Functional | Antimutagenic activity against Vibrio harveyi BB7M assessed as inhibition of NQNO-induced mutagenicity after 48 hrs | Vibrio harveyi | 9 | ALA3774372 | organism-based format | Scientific Literature | |
8. | ALA3777282 | Functional | Antimutagenic activity against Vibrio harveyi BB7XM assessed as inhibition of NQNO-induced mutagenicity after 48 hrs | Vibrio harveyi | 9 | ALA3774372 | organism-based format | Scientific Literature | |
9. | ALA3777283 | ADME | Retention time of the compound in mouse liver microsomes at 20 uM preincubated for 15 mins followed by addition of NADPH-regenerating system measured after 5 to 90 mins by UPLC/MC analysis | Mus musculus | 3 | ALA3774372 | tissue-based format | Scientific Literature | |
10. | ALA3777284 | ADME | Half life in mouse liver microsomes at 20 uM preincubated for 15 mins followed by addition of NADPH-regenerating system measured after 5 to 90 mins by UPLC/MC analysis | Mus musculus | 5 | ALA3774372 | tissue-based format | Scientific Literature | |
11. | ALA3777285 | ADME | Intrinsic clearance in mouse liver microsomes at 20 uM preincubated for 15 mins followed by addition of NADPH-regenerating system measured after 5 to 90 mins by UPLC/MC analysiS | Mus musculus | 5 | ALA3774372 | tissue-based format | Scientific Literature | |
12. | ALA3777288 | ADME | Drug metabolism in mouse liver microsomes assessed as formation of M1 metabolite at 20 uM preincubated for 15 mins followed by addition of NADPH-regenerating system measured after 5 to 90 mins by UPLC/MC analysis | Mus musculus | 3 | ALA3774372 | tissue-based format | Scientific Literature | |
13. | ALA3777289 | ADME | Drug metabolism in mouse liver microsomes assessed as formation of M2 metabolite at 20 uM preincubated for 15 mins followed by addition of NADPH-regenerating system measured after 5 to 90 mins by UPLC/MC analysis | Mus musculus | 3 | ALA3774372 | tissue-based format | Scientific Literature | |
14. | ALA3777290 | ADME | Drug metabolism in mouse liver microsomes assessed as formation of M3 metabolite at 20 uM preincubated for 15 mins followed by addition of NADPH-regenerating system measured after 5 to 90 mins by UPLC/MC analysis | Mus musculus | 2 | ALA3774372 | tissue-based format | Scientific Literature | |
15. | ALA3776919 | Functional | Anticonvulsant activity in mouse assessed as protection against maximal electric shock-induced seizures at 30 mg/kg, ip measured after 0.5 hrs | Mus musculus | 24 | ALA3774372 | organism-based format | Scientific Literature | |
16. | ALA3776921 | Functional | Anticonvulsant activity in mouse assessed as protection against maximal electric shock-induced seizures at 30 mg/kg, ip measured after 4 hrs | Mus musculus | 25 | ALA3774372 | organism-based format | Scientific Literature | |
17. | ALA3776922 | Functional | Anticonvulsant activity in mouse assessed as protection against maximal electric shock-induced seizures at 100 mg/kg, ip measured after 0.5 hrs | Mus musculus | 17 | ALA3774372 | organism-based format | Scientific Literature | |
18. | ALA3776930 | Functional | Anticonvulsant activity in mouse assessed as protection against subcutaneous pentylenetetrazol-induced seizures at 30 mg/kg, ip measured after 0.5 hrs | Mus musculus | 23 | ALA3774372 | organism-based format | Scientific Literature | |
19. | ALA3776931 | Functional | Anticonvulsant activity in mouse assessed as protection against subcutaneous pentylenetetrazol-induced seizures at 100 mg/kg, ip measured after 0.5 hrs | Mus musculus | 14 | ALA3774372 | organism-based format | Scientific Literature | |
20. | ALA3776933 | Functional | Anticonvulsant activity in mouse assessed as protection against subcutaneous pentylenetetrazol-induced seizures at 30 mg/kg, ip measured after 4 hrs | Mus musculus | 23 | ALA3774372 | organism-based format | Scientific Literature |