| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3778678 | B | Inhibition of Flag-tagged p53/GST-tagged Mdm2 (unknown origin) expressed in Escherichia coli BL21 after 1 hr by ELISA microplate reader method | Homo sapiens | 10 | ALA3774315 | assay format | Scientific Literature | |
| 2. | ALA3778679 | B | Inhibition of Flag-tagged p53/GST-tagged Mdmx (unknown origin) expressed in Escherichia coli BL21 after 1 hr by ELISA microplate reader method | Homo sapiens | 10 | ALA3774315 | assay format | Scientific Literature | |
| 3. | ALA3778680 | B | Inhibition of Flag-tagged p53/GST-tagged DAPK1 (unknown origin) expressed in Escherichia coli BL21 after 1 hr by ELISA microplate reader method | Homo sapiens | 10 | ALA3774315 | assay format | Scientific Literature | |
| 4. | ALA3778681 | B | Inhibition of Flag-tagged p53/GST-tagged PPID (unknown origin) expressed in Escherichia coli BL21 after 1 hr by ELISA microplate reader method | Homo sapiens | 10 | ALA3774315 | assay format | Scientific Literature | |
| 5. | ALA3778682 | F | Cytotoxicity against human MCF7 cells expressing WT p53 and Mdmx assessed as growth inhibition after 48 hrs by crystal violet staining based spectrophotometry | Homo sapiens | 2 | ALA3774315 | cell-based format | Scientific Literature | |
| 6. | ALA3778683 | F | Cytotoxicity against human A427 cells expressing WT p53 and Mdmx assessed as growth inhibition after 48 hrs by crystal violet staining based spectrophotometry | Homo sapiens | 2 | ALA3774315 | cell-based format | Scientific Literature | |
| 7. | ALA3778886 | F | Cytotoxicity against human HCT116 cells expressing WT p53 and Mdmx assessed as growth inhibition after 48 hrs by crystal violet staining based spectrophotometry | Homo sapiens | 2 | ALA3774315 | cell-based format | Scientific Literature | |
| 8. | ALA3778887 | F | Cytotoxicity against human A431 cells expressing mutant p53 assessed as growth inhibition after 48 hrs by crystal violet staining based spectrophotometry | Homo sapiens | 2 | ALA3774315 | cell-based format | Scientific Literature | |
| 9. | ALA3778888 | F | Cytotoxicity against human MDA-MB-468 cells expressing mutant p53 assessed as growth inhibition after 48 hrs by crystal violet staining based spectrophotometry | Homo sapiens | 2 | ALA3774315 | cell-based format | Scientific Literature | |
| 10. | ALA3778889 | A | Cytotoxicity against human TIG7 cells expressing mutant p53 assessed as growth inhibition after 48 hrs by crystal violet staining based spectrophotometry | Homo sapiens | 1 | ALA3774315 | cell-based format | Scientific Literature | |
| 11. | ALA3778890 | F | Upregulation of p53 in human MCF7 cells after 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA3774315 | cell-based format | Scientific Literature | |
| 12. | ALA3778891 | F | Upregulation of p21 in human MCF7 cells after 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA3774315 | cell-based format | Scientific Literature | |
| 13. | ALA3778892 | F | Upregulation of Mdm2 in human MCF7 cells after 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA3774315 | cell-based format | Scientific Literature | |
| 14. | ALA3778893 | F | Increase in p53 expression in human IMR32 cells nuclei after 24 hrs by DAPI staining based immunofluorescence microscopy | Homo sapiens | 2 | ALA3774315 | cell-based format | Scientific Literature | |
| 15. | ALA3778894 | F | Increase in p53 expression in human MCF7 cells nuclei after 24 hrs by DAPI staining based immunofluorescence microscopy | Homo sapiens | 2 | ALA3774315 | cell-based format | Scientific Literature | |
| 16. | ALA3778895 | F | Antitumor activity against human HCT116 cells xenografted in nude BALB/c mouse assessed as decrease in tumor growth at 100 mg/kg/day, po administered every other day until day 38 and measured on day 40 | Homo sapiens | 1 | ALA3774315 | organism-based format | Scientific Literature | |
| 17. | ALA3778897 | T | Toxicity in human HCT116 cells xenografted nude BALB/c mouse assessed as body weight loss at 100 mg/kg/day, po administered every other day until day 38 and measured on day 40 | Mus musculus | 1 | ALA3774315 | organism-based format | Scientific Literature | |
| 18. | ALA3778898 | F | Upregulation of Mdm2 protein expression in human HCT116 cells xenografted nude BALB/c mouse tumors at 150 mg/kg/day, po administered every other day until day 38 and measured on day 40 by Western blot analysis | Mus musculus | 1 | ALA3774315 | organism-based format | Scientific Literature | |
| 19. | ALA3778899 | F | Upregulation of p53 protein expression in human HCT116 cells xenografted nude BALB/c mouse tumors at 150 mg/kg/day, po administered every other day until day 38 and measured on day 40 by Western blot analysis | Mus musculus | 1 | ALA3774315 | organism-based format | Scientific Literature | |
| 20. | ALA3778900 | F | Upregulation of p21 protein expression in human HCT116 cells xenografted nude BALB/c mouse tumors at 150 mg/kg/day, po administered every other day until day 38 and measured on day 40 by Western blot analysis | Mus musculus | 1 | ALA3774315 | organism-based format | Scientific Literature |
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