# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3776565 | F | Cytotoxicity against human K562 cells assessed as cell viability after 72 hrs by MTT assay | Homo sapiens | 20 | ALA3774352 | cell-based format | Scientific Literature | |
2. | ALA3776566 | F | Cytotoxicity against human K562/G cells assessed as cell viability after 72 hrs by MTT assay | Homo sapiens | 16 | ALA3774352 | cell-based format | Scientific Literature | |
3. | ALA3776808 | F | Potency index, ratio IC50 of imatinib to IC50 of compound for cytotoxicity against human K562 cells | Homo sapiens | 1 | ALA3774352 | cell-based format | Scientific Literature | |
4. | ALA3776809 | F | Potency index, ratio IC50 of imatinib to IC50 of compound for cytotoxicity against human K562/G cells | Homo sapiens | 1 | ALA3774352 | cell-based format | Scientific Literature | |
5. | ALA3776810 | A | Cytotoxicity against mouse BA/F3 cells expressing BCR-ABL T315I mutant after 72 hrs by MTT assay | Mus musculus | 6 | ALA3774352 | cell-based format | Scientific Literature | |
6. | ALA3776811 | A | Cytotoxicity against normal human hematopoietic stem cells after 24 hrs by MTT assay | Homo sapiens | 2 | ALA3774352 | cell-based format | Scientific Literature | |
7. | ALA3776812 | F | Induction of apoptosis in human K562 cells at 0.25 to 0.5 uM after 72 hrs by AnnexinV-APC/Propidium iodide based flow cytometry | Homo sapiens | 1 | ALA3774352 | cell-based format | Scientific Literature | |
8. | ALA3776813 | F | Induction of apoptosis in human K562 cells assessed as downregulation of caspase-3 expression at 0.1 uM after 72 hrs by Western Blot analysis | Homo sapiens | 1 | ALA3774352 | cell-based format | Scientific Literature | |
9. | ALA3776814 | F | Induction of apoptosis in human K562 cells assessed as downregulation of caspase-3 expression at 0.25 uM after 72 hrs by Western Blot analysis | Homo sapiens | 1 | ALA3774352 | cell-based format | Scientific Literature | |
10. | ALA3776815 | F | Induction of apoptosis in human K562 cells assessed as downregulation of PARP expression at 0.1 uM after 72 hrs by Western Blot analysis | Homo sapiens | 1 | ALA3774352 | cell-based format | Scientific Literature | |
11. | ALA3776816 | F | Induction of apoptosis in human K562 cells assessed as downregulation of PARP protein expression at 0.25 uM after 72 hrs by Western Blot analysis | Homo sapiens | 1 | ALA3774352 | cell-based format | Scientific Literature | |
12. | ALA3776818 | U | Resistance index, ratio IC50 for mouse BA/F3 cells expressing BCR-ABL T315I mutant to IC50 for human K562 cells | 6 | ALA3774352 | cell-based format | Scientific Literature | ||
13. | ALA3993666 | F | Cytotoxicity against human MCF7 cells incubated for 72 hrs under normoxic condition by MTT assay | Homo sapiens | 11 | ALA3992529 | cell-based format | Scientific Literature | |
14. | ALA3993667 | F | Cytotoxicity against human MCF7 cells incubated for 72 hrs under hypoxic condition by MTT assay | Homo sapiens | 11 | ALA3992529 | cell-based format | Scientific Literature | |
15. | ALA3993668 | F | Selectivity index, ratio of IC50 for human MCF7 cells under hypoxic condition to IC50 for human MCF7 cells under normoxic condition | Homo sapiens | 10 | ALA3992529 | cell-based format | Scientific Literature | |
16. | ALA4153475 | F | Cytotoxicity against human PANC1 cells after 72 hrs under hypoxic condition by MTT assay | Homo sapiens | 25 | ALA4152216 | cell-based format | Scientific Literature | |
17. | ALA4153476 | F | Cytotoxicity against human PANC1 cells after 72 hrs under normoxic condition by MTT assay | Homo sapiens | 25 | ALA4152216 | cell-based format | Scientific Literature | |
18. | ALA4153477 | F | Selectivity index, ratio of IC50 against human PANC1 cells under normoxic condition to IC50 for human PANC1 cells under hypoxic condition | Homo sapiens | 23 | ALA4152216 | cell-based format | Scientific Literature | |
19. | ALA4153478 | F | Cytotoxicity against human Aspc-1 cells after 72 hrs under normoxic condition by MTT assay | Homo sapiens | 14 | ALA4152216 | cell-based format | Scientific Literature | |
20. | ALA4153479 | F | Cytotoxicity against human Aspc-1 cells after 72 hrs under hypoxic condition by MTT assay | Homo sapiens | 14 | ALA4152216 | cell-based format | Scientific Literature |