# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3776182 | B | Inhibition of CDK2 in human G361 cells assessed as reduction in phosphorylation of RNA polymerase 2 at C-terminus at 0.1 to 1 uM incubated for 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA3774312 | cell-based format | Scientific Literature | |
2. | ALA3776183 | B | Inhibition of CDK4 (unknown origin) | Homo sapiens | 4 | ALA3774312 | single protein format | Scientific Literature | |
3. | ALA3777409 | B | Inhibition of CDK2/Cyclin E (unknown origin) expressed in sf9 cells using histone H1 as substrate in presence of [gamma33P]-ATP | Homo sapiens | 25 | ALA3774312 | cell-based format | Scientific Literature | |
4. | ALA3777410 | B | Inhibition of CDK1 (unknown origin) | Homo sapiens | 4 | ALA3774312 | single protein format | Scientific Literature | |
5. | ALA3777411 | F | Cell cycle arrest in BrdU pulse-labelled human MCF7 cells assessed as accumulation at late G2/M phase at 8 to 250 nM after 24 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 2 | ALA3774312 | cell-based format | Scientific Literature | |
6. | ALA3777412 | B | Inhibition of CDK5 (unknown origin) using histone H1 as substrate in presence of [gamma33P]-ATP | Homo sapiens | 25 | ALA3774312 | single protein format | Scientific Literature | |
7. | ALA3777413 | B | Inhibition of recombinant CAMKKB (unknown origin) assessed as residual activity at 1 uM relative to control | Homo sapiens | 1 | ALA3774312 | single protein format | Scientific Literature | |
8. | ALA3777414 | B | Inhibition of recombinant DYRK1A (unknown origin) assessed as residual activity at 1 uM relative to control | Homo sapiens | 1 | ALA3774312 | single protein format | Scientific Literature | |
9. | ALA3777415 | B | Inhibition of recombinant CK1delta (unknown origin) assessed as residual activity at 1 uM relative to control | Homo sapiens | 1 | ALA3774312 | single protein format | Scientific Literature | |
10. | ALA3777416 | B | Inhibition of recombinant human AMPK assessed as residual activity at 1 uM relative to control | Homo sapiens | 1 | ALA3774312 | protein complex format | Scientific Literature | |
11. | ALA3777417 | B | Inhibition of recombinant PAK4 (unknown origin) assessed as residual activity at 1 uM relative to control | Homo sapiens | 1 | ALA3774312 | single protein format | Scientific Literature | |
12. | ALA3777418 | B | Inhibition of recombinant CAMK1 (unknown origin) assessed as residual activity at 1 uM relative to control | Homo sapiens | 1 | ALA3774312 | single protein format | Scientific Literature | |
13. | ALA3777419 | B | Inhibition of recombinant RSK1 (unknown origin) assessed as residual activity at 1 uM relative to control | Homo sapiens | 1 | ALA3774312 | single protein format | Scientific Literature | |
14. | ALA3777420 | B | Inhibition of recombinant CHK2 (unknown origin) assessed as residual activity at 1 uM relative to control | Homo sapiens | 1 | ALA3774312 | single protein format | Scientific Literature | |
15. | ALA3777655 | F | Cytotoxicity against human K562 cells assessed as reduction in cell viability after 72 hrs by calcein AM staining based fluorescence assay | Homo sapiens | 22 | ALA3774312 | cell-based format | Scientific Literature | |
16. | ALA3777656 | F | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by calcein AM staining based fluorescence assay | Homo sapiens | 22 | ALA3774312 | cell-based format | Scientific Literature | |
17. | ALA3777657 | F | Cytotoxicity against human G361 cells assessed as reduction in cell viability after 72 hrs by calcein AM staining based fluorescence assay | Homo sapiens | 22 | ALA3774312 | cell-based format | Scientific Literature | |
18. | ALA3777658 | F | Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by calcein AM staining based fluorescence assay | Homo sapiens | 22 | ALA3774312 | cell-based format | Scientific Literature | |
19. | ALA3777659 | B | Inhibition of CDK7 (unknown origin) | Homo sapiens | 3 | ALA3774312 | single protein format | Scientific Literature | |
20. | ALA3777660 | B | Inhibition of CDK9 (unknown origin) | Homo sapiens | 4 | ALA3774312 | single protein format | Scientific Literature |