# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3779189 | B | Inhibition of CDK8 (unknown origin) expressed in 7dF3 clone of human HEK293 cells preincubated for 2 hrs followed by addition of beta-estradiol by luciferase assay | Homo sapiens | 32 | ALA3774357 | cell-based format | Scientific Literature | |
2. | ALA3779190 | B | Inhibition of Hsp90 (unknown origin) assessed as remaining activity at 4 uM | Homo sapiens | 7 | ALA3774357 | protein format | Scientific Literature | |
3. | ALA3779191 | B | Displacement of dye-labeled ATP competitive probe from recombinant human CDK8/Cyclin C incubated for 20 mins by Alexa647 probe-based FRET assay | Homo sapiens | 32 | ALA3774357 | protein complex format | Scientific Literature | |
4. | ALA3779192 | A | Intrinsic clearance in human liver microsomes assessed per mg protein | Homo sapiens | 32 | ALA3774357 | tissue-based format | Scientific Literature | |
5. | ALA3779193 | A | Intrinsic clearance in rat liver microsomes assessed per mg protein | Rattus norvegicus | 32 | ALA3774357 | tissue-based format | Scientific Literature | |
6. | ALA3779195 | A | Intrinsic clearance in mouse liver microsomes assessed per mg protein | Mus musculus | 32 | ALA3774357 | tissue-based format | Scientific Literature | |
7. | ALA3779196 | P | Kinetic solubility of the compound | 32 | ALA3774357 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA3779197 | P | Thermodynamic solubility of the compound | 3 | ALA3774357 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA3779198 | A | Apparent permeability from apical to basolateral side in human Caco2 cells | Homo sapiens | 18 | ALA3774357 | cell-based format | Scientific Literature | |
10. | ALA3779199 | A | Efflux ratio of apparent permeability in human Caco2 cells | Homo sapiens | 18 | ALA3774357 | cell-based format | Scientific Literature | |
11. | ALA5241254 | B | Inhibition of CDK8 (unknown origin) | Homo sapiens | 10 | ALA5241055 | single protein format | Scientific Literature | |
12. | ALA5241264 | B | Inhibition of HSP90 (unknown origin) | Homo sapiens | 3 | ALA5241055 | protein format | Scientific Literature |