# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3776305 | Functional | Antiproliferative activity against mouse L1210 cells after 48 hrs by MTT assay | Mus musculus | 15 | ALA3774310 | cell-based format | Scientific Literature | |
2. | ALA3776306 | Functional | Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay | Homo sapiens | 15 | ALA3774310 | cell-based format | Scientific Literature | |
3. | ALA3776307 | Functional | Antiproliferative activity against human K562 cells after 72 hrs by MTT assay | Homo sapiens | 15 | ALA3774310 | cell-based format | Scientific Literature | |
4. | ALA3776308 | Functional | Antiproliferative activity against human K562/4 cells after 72 hrs by MTT assay | Homo sapiens | 15 | ALA3774310 | cell-based format | Scientific Literature | |
5. | ALA3776309 | Functional | Resistance index, ratio of IC50 for human K562/4 cells to IC50 for human K562 cells | Homo sapiens | 15 | ALA3774310 | cell-based format | Scientific Literature | |
6. | ALA3776310 | Functional | Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay | Homo sapiens | 15 | ALA3774310 | cell-based format | Scientific Literature | |
7. | ALA3776311 | Functional | Antiproliferative activity against p53 knockout human HCT116 cells after 72 hrs by MTT assay | Homo sapiens | 15 | ALA3774310 | cell-based format | Scientific Literature | |
8. | ALA3776312 | Functional | Resistance index, ratio of IC50 for p53 knockout human HCT116 cells to IC50 for parental human HCT116 cells | Homo sapiens | 15 | ALA3774310 | cell-based format | Scientific Literature | |
9. | ALA3776313 | ADME | Cytotoxicity against hFB-hTERT6 assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 2 | ALA3774310 | assay format | Scientific Literature | |
10. | ALA3777827 | ADME | Cytotoxicity against human PBL assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 2 | ALA3774310 | cell-based format | Scientific Literature | |
11. | ALA3777828 | Binding | Binding affinity to P-gp in human K562 cells assessed as drug accumulation at 1 uM incubated for 1 to 24 hrs by flow cytometry | Homo sapiens | 3 | ALA3774310 | cell-based format | Scientific Literature | |
12. | ALA3777829 | Binding | Binding affinity to P-gp in human K562/4 cells assessed as drug accumulation at 1 uM incubated for 1 to 24 hrs by flow cytometry | Homo sapiens | 3 | ALA3774310 | cell-based format | Scientific Literature | |
13. | ALA3777830 | Functional | Cell cycle arrest in human HCT116 cells assessed as accumulation in G2/M phase at 1 uM after 24 hrs | Homo sapiens | 2 | ALA3774310 | cell-based format | Scientific Literature | |
14. | ALA3777831 | Functional | Cell cycle arrest in p53 knockout human HCT116 cells assessed as accumulation in G2/M phase at 1 uM after 24 hrs | Homo sapiens | 2 | ALA3774310 | cell-based format | Scientific Literature | |
15. | ALA3777832 | Functional | Induction of apoptosis in human HCT116 cells assessed as viable cells at 1 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based assay (Rvb = 95 +/- 2%) | Homo sapiens | 2 | ALA3774310 | cell-based format | Scientific Literature | |
16. | ALA3777833 | Functional | Induction of apoptosis in human HCT116 cells assessed as viable cells at 1 uM after 48 hrs by Annexin V-FITC/propidium iodide staining based assay (Rvb = 95 +/- 2%) | Homo sapiens | 2 | ALA3774310 | cell-based format | Scientific Literature | |
17. | ALA3777834 | Functional | Cell cycle arrest in human HCT116 cells assessed as accumulation in sub G1 phase at 1 uM after 24 to 48 hrs relative to control | Homo sapiens | 2 | ALA3774310 | cell-based format | Scientific Literature | |
18. | ALA3777835 | Functional | Cell cycle arrest in p53 knockout human HCT116 cells assessed as accumulation in sub G1 phase at 1 uM after 24 to 48 hrs relative to control | Homo sapiens | 2 | ALA3774310 | cell-based format | Scientific Literature | |
19. | ALA3777836 | Functional | Cell cycle arrest in human HCT116 cells assessed as decrease in G1 phase at 1 uM after 24 hrs | Homo sapiens | 2 | ALA3774310 | cell-based format | Scientific Literature | |
20. | ALA3777837 | Functional | Cell cycle arrest in p53 knockout human HCT116 cells assessed as decrease in G1 phase at 1 uM after 24 hrs | Homo sapiens | 2 | ALA3774310 | cell-based format | Scientific Literature |