| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3776776 | B | Antagonist activity against 6xHis-MBP-fused human MR LBD domain (732 to 984 amino acid residues) C808S mutant expressed in Escherichia coli BL21(DE3) assessed as inhibition of aldosterone-mediated receptor activation after 16 hrs by luciferase assay | Homo sapiens | 26 | ALA3774336 | assay format | Scientific Literature | |
| 2. | ALA3776777 | B | Displacement of 3H-Cortisol from 6xHis-MBP-fused human MR LBD domain (732 to 984 amino acid residues) C808S mutant expressed in Escherichia coli BL21(DE3) preincubated for 1 hr measured after 30 mins by microbeta plate reader analysis | Homo sapiens | 26 | ALA3774336 | assay format | Scientific Literature | |
| 3. | ALA3776779 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 8 | ALA3774336 | single protein format | Scientific Literature | |
| 4. | ALA3776780 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 8 | ALA3774336 | single protein format | Scientific Literature | |
| 5. | ALA3776781 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 8 | ALA3774336 | single protein format | Scientific Literature | |
| 6. | ALA3776782 | B | Inhibition of serotonin 5H2B receptor (unknown origin) at 10 uM | Homo sapiens | 9 | ALA3774336 | single protein format | Scientific Literature | |
| 7. | ALA3776783 | B | Inhibition of histamine H1 receptor (unknown origin) at 10 uM | Homo sapiens | 9 | ALA3774336 | single protein format | Scientific Literature | |
| 8. | ALA3776784 | B | Inhibition of human ERG (unknown origin) at 10 uM | Homo sapiens | 9 | ALA3774336 | single protein format | Scientific Literature | |
| 9. | ALA3776785 | B | Inhibition of adrenergic alpha2A receptor (unknown origin) at 10 uM | Homo sapiens | 9 | ALA3774336 | single protein format | Scientific Literature | |
| 10. | ALA3776786 | A | Half life of compound in rat liver microsomes | Rattus norvegicus | 6 | ALA3774336 | tissue-based format | Scientific Literature | |
| 11. | ALA3778067 | B | Inhibition of GST-tagged human progesterone receptor LBD domain expressed in insect cells by Gal4-based fluorescence polarization assay | Homo sapiens | 5 | ALA3774336 | cell-based format | Scientific Literature | |
| 12. | ALA3778068 | B | Inhibition of GST-tagged human glucocorticoid receptor LBD domain expressed in insect cells at by Gal4-based fluorescence polarization assay | Homo sapiens | 5 | ALA3774336 | cell-based format | Scientific Literature | |
| 13. | ALA3778069 | B | Inhibition of estrogen receptor (unknown origin) by Gal4-based luciferase assay | Homo sapiens | 5 | ALA3774336 | single protein format | Scientific Literature | |
| 14. | ALA3778070 | B | Selectivity ratio of IC50 for GST-tagged human glucocorticoid receptor LBD domain expressed in insect cells to IC50 for 6xHis-MBP-fused human MR LBD domain (732 to 984 amino acid residues) C808S mutant | Homo sapiens | 3 | ALA3774336 | cell-based format | Scientific Literature | |
| 15. | ALA3778071 | B | Selectivity ratio of IC50 for GST-tagged human progesterone receptor LBD domain expressed in insect cells to IC50 for 6xHis-MBP-fused human MR LBD domain (732 to 984 amino acid residues) C808S mutant | Homo sapiens | 3 | ALA3774336 | cell-based format | Scientific Literature | |
| 16. | ALA3778072 | B | Selectivity ratio of IC50 for estrogen receptor (unknown origin) to IC50 for 6xHis-MBP-fused human MR LBD domain (732 to 984 amino acid residues) C808S mutant | Homo sapiens | 3 | ALA3774336 | assay format | Scientific Literature |
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