# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3784639 | B | Selectivity ratio of EC50 for mouse TRH-R1 to EC50 for mouse TRH-R2 by ELISA | Mus musculus | 14 | ALA3779763 | assay format | Scientific Literature | |
2. | ALA3784640 | B | Displacement of [3H]-Me-His-TRH from mouse TRH-R1 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrs | Mus musculus | 16 | ALA3779763 | cell-based format | Scientific Literature | |
3. | ALA3784641 | B | Displacement of [3H]-Me-His-TRH from mouse TRH-R2 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrs | Mus musculus | 16 | ALA3779763 | cell-based format | Scientific Literature | |
4. | ALA3784642 | B | Selectivity index, ratio of IC50 for mouse TRH-R1 to IC50 for mouse TRH-R2 | Mus musculus | 8 | ALA3779763 | assay format | Scientific Literature | |
5. | ALA3784643 | F | Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assay | Mus musculus | 16 | ALA3779763 | cell-based format | Scientific Literature | |
6. | ALA3784644 | F | Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assay | Mus musculus | 16 | ALA3779763 | cell-based format | Scientific Literature | |
7. | ALA3784645 | B | Selectivity ratio of EC50 for mouse TRH-R1 to EC50 for mouse TRH-R2 by FLIPR assay | Mus musculus | 14 | ALA3779763 | assay format | Scientific Literature | |
8. | ALA3784646 | F | Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISA | Mus musculus | 16 | ALA3779763 | cell-based format | Scientific Literature | |
9. | ALA3784647 | F | Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISA | Mus musculus | 16 | ALA3779763 | cell-based format | Scientific Literature | |
10. | ALA3784648 | F | Reversal of pentobarbital-induced sleeping time in albino Swiss mouse at 10 umol/kg, iv administered 10 mins prior to pentobarbital injection | Mus musculus | 16 | ALA3779763 | organism-based format | Scientific Literature | |
11. | ALA3784649 | B | Displacement of [3H]-Me-His-TRH from wild type TRHR mouse brain membranes at 10 uM after 4 hrs by scintillation counting method | Mus musculus | 2 | ALA3779763 | tissue-based format | Scientific Literature | |
12. | ALA3784650 | B | Displacement of [3H]-Me-His-TRH from wild type TRHR mouse brain membranes at 1 uM after 4 hrs by scintillation counting method | Mus musculus | 2 | ALA3779763 | tissue-based format | Scientific Literature | |
13. | ALA3784651 | B | Displacement of [3H]-Me-His-TRH from wild type TRHR mouse brain membranes at 0.1 uM after 4 hrs by scintillation counting method | Mus musculus | 2 | ALA3779763 | tissue-based format | Scientific Literature | |
14. | ALA3784652 | B | Displacement of [3H]-Me-His-TRH from wild type TRHR mouse brain membranes at 0.01 uM after 4 hrs by scintillation counting method | Mus musculus | 2 | ALA3779763 | tissue-based format | Scientific Literature | |
15. | ALA3784653 | B | Displacement of [3H]-Me-His-TRH from wild type TRHR mouse brain membrane at 30 uM after 4 hrs by scintillation counting method | Mus musculus | 1 | ALA3779763 | tissue-based format | Scientific Literature | |
16. | ALA3784654 | B | Displacement of [3H]-Me-His-TRH from wild type TRHR mouse brain membrane at 3 uM after 4 hrs by scintillation counting method | Mus musculus | 1 | ALA3779763 | tissue-based format | Scientific Literature | |
17. | ALA3784655 | B | Displacement of [2,5-125I2]-Me-His-TRH from wild type TRHR mouse brain membranes at 30 uM after 4 hrs by scintillation counting method | Mus musculus | 1 | ALA3779763 | tissue-based format | Scientific Literature | |
18. | ALA3784656 | B | Displacement of [2,5-125I2]-Me-His-TRH from wild type TRHR mouse brain membranes at 10 uM after 4 hrs by scintillation counting method | Mus musculus | 1 | ALA3779763 | tissue-based format | Scientific Literature | |
19. | ALA3784657 | B | Displacement of [2,5-125I2]-Me-His-TRH from wild type TRHR mouse brain membranes at 3 uM after 4 hrs by scintillation counting method | Mus musculus | 1 | ALA3779763 | tissue-based format | Scientific Literature | |
20. | ALA3784764 | B | Displacement of [2,5-125I2]-Me-His-TRH from wild type TRHR mouse brain membranes at 1 uM after 4 hrs by scintillation counting method | Mus musculus | 1 | ALA3779763 | tissue-based format | Scientific Literature |