# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3783756 | Functional | Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer | Homo sapiens | 38 | ALA3779872 | cell-based format | Scientific Literature | |
2. | ALA3783757 | Functional | Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer relative to phenethylamine | Homo sapiens | 37 | ALA3779872 | cell-based format | Scientific Literature | |
3. | ALA3783758 | Binding | Selectivity ratio of EC50 for human adrenergic alpha 2A receptor expressed in CHL cells to EC50 for human TAAR1 expressed in recombinant HEK293 cells | Homo sapiens | 38 | ALA3779872 | cell-based format | Scientific Literature | |
4. | ALA3783759 | Functional | Agonist activity at rat TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer | Rattus norvegicus | 17 | ALA3779872 | cell-based format | Scientific Literature | |
5. | ALA3783760 | Functional | Agonist activity at rat TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer relative to phenethylamine | Rattus norvegicus | 14 | ALA3779872 | cell-based format | Scientific Literature | |
6. | ALA3783762 | ADME | Clearance in human liver microsomes | Homo sapiens | 7 | ALA3779872 | tissue-based format | Scientific Literature | |
7. | ALA3783763 | ADME | Clearance in human hepatocytes | Homo sapiens | 7 | ALA3779872 | cell-based format | Scientific Literature |