# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3782730 | Binding | Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in presence of oxidative phosphorylation inhibitor rotenone | Homo sapiens | 57 | ALA3779893 | cell-based format | Scientific Literature | |
2. | ALA3782731 | Binding | Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in presence of oxidative phosphorylation inhibitor rotenone | Homo sapiens | 57 | ALA3779893 | cell-based format | Scientific Literature | |
3. | ALA3782732 | Binding | Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter-Glo assay in presence of oxidative phosphorylation inhibitor rotenone | Homo sapiens | 57 | ALA3779893 | cell-based format | Scientific Literature | |
4. | ALA3782733 | ADME | Intrinsic clearance in rat hepatocytes | Rattus norvegicus | 4 | ALA3779893 | cell-based format | Scientific Literature | |
5. | ALA3782734 | ADME | Intrinsic clearance in human liver microsomes | Homo sapiens | 5 | ALA3779893 | tissue-based format | Scientific Literature | |
6. | ALA3782738 | ADME | Apparent permeability from apical to basolateral side in human Caco2 cells at 2 uM after 2 hrs | Homo sapiens | 3 | ALA3779893 | cell-based format | Scientific Literature | |
7. | ALA3782739 | ADME | Efflux ratio of apparent permeability from basolateral to apical side over apical to basolateral side in human Caco2 cells | Homo sapiens | 3 | ALA3779893 | cell-based format | Scientific Literature |