# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3784476 | B | Inhibition of human coagulation factor 9a assessed as reduction in release of p-nitroaniline after 10 to 120 mins by Michaelis-Menten equation analysis | Homo sapiens | 4 | ALA3779805 | single protein format | Scientific Literature | |
2. | ALA3784477 | B | Inhibition of human coagulation factor 7a assessed as reduction in release of p-nitroaniline after 10 to 120 mins by Michaelis-Menten equation analysis | Homo sapiens | 4 | ALA3779805 | single protein format | Scientific Literature | |
3. | ALA3784478 | B | Competitive inhibition of human coagulation factor 11a assessed as reduction in release of p-nitroaniline after 10 to 120 mins by Michaelis-Menten equation analysis | Homo sapiens | 32 | ALA3779805 | single protein format | Scientific Literature | |
4. | ALA3784479 | A | Oral bioavailability in beagle dog plasma at 1 mg/kg dosed in discrete format by LC-MS/MS method | Canis lupus familiaris | 1 | ALA3779805 | organism-based format | Scientific Literature | |
5. | ALA3784480 | F | Anticoagulant activity in human plasma assessed as concentration required for 50% increase in activated partial thromboplastin time by automated coagulation analyzer | Homo sapiens | 31 | ALA3779805 | cell-free format | Scientific Literature | |
6. | ALA3784586 | A | Clearance in beagle dog plasma at 0.25 mg/kg, iv and 0.2 mg/kg, po administered in cassette format by LC-MS/MS method | Canis lupus familiaris | 1 | ALA3779805 | organism-based format | Scientific Literature | |
7. | ALA3784592 | A | Half life in beagle dog plasma at 0.25 mg/kg, iv and 0.2 mg/kg, po by LC-MS/MS method | Canis lupus familiaris | 1 | ALA3779805 | organism-based format | Scientific Literature | |
8. | ALA3783197 | A | Volume of distribution at steady state in beagle dog plasma at 0.25 mg/kg, iv and 0.2 mg/kg, po by LC-MS/MS method | Canis lupus familiaris | 1 | ALA3779805 | organism-based format | Scientific Literature | |
9. | ALA3783203 | A | Oral bioavailability in beagle dog plasma at 0.2 mg/kg by LC-MS/MS method | Canis lupus familiaris | 4 | ALA3779805 | organism-based format | Scientific Literature | |
10. | ALA3783210 | A | AUC in beagle dog plasma at 0.25 mg/kg, iv and 0.2 mg/kg, po by LC-MS/MS method | Canis lupus familiaris | 1 | ALA3779805 | organism-based format | Scientific Literature | |
11. | ALA3783212 | A | AUC in beagle dog plasma at 1 mg/kg, po dosed in discrete format by LC-MS/MS method | Canis lupus familiaris | 1 | ALA3779805 | organism-based format | Scientific Literature | |
12. | ALA3783213 | B | Inhibition of human coagulation factor 10a assessed as reduction in release of p-nitroaniline after 10 to 120 mins by Michaelis-Menten equation analysis | Homo sapiens | 4 | ALA3779805 | single protein format | Scientific Literature | |
13. | ALA3783214 | B | Inhibition of human coagulation thrombin assessed as reduction in release of p-nitroaniline after 10 to 120 mins by Michaelis-Menten equation analysis | Homo sapiens | 4 | ALA3779805 | single protein format | Scientific Literature | |
14. | ALA3783215 | B | Inhibition of human coagulation trypsin assessed as reduction in release of p-nitroaniline after 10 to 120 mins by Michaelis-Menten equation analysis | Homo sapiens | 4 | ALA3779805 | protein format | Scientific Literature | |
15. | ALA3783216 | B | Inhibition of human plasma kallikrein assessed as reduction in release of p-nitroaniline after 10 to 120 mins by Michaelis-Menten equation analysis | Homo sapiens | 4 | ALA3779805 | cell-free format | Scientific Literature | |
16. | ALA3783217 | B | Inhibition of human activated protein C assessed as reduction in release of p-nitroaniline after 10 to 120 mins by Michaelis-Menten equation analysis | Homo sapiens | 4 | ALA3779805 | single protein format | Scientific Literature | |
17. | ALA3783218 | B | Inhibition of human plasmin assessed as reduction in release of p-nitroaniline after 10 to 120 mins by Michaelis-Menten equation analysis | Homo sapiens | 4 | ALA3779805 | single protein format | Scientific Literature | |
18. | ALA3783219 | B | Inhibition of human TPA assessed as reduction in release of p-nitroaniline after 10 to 120 mins by Michaelis-Menten equation analysis | Homo sapiens | 4 | ALA3779805 | single protein format | Scientific Literature | |
19. | ALA3783220 | B | Inhibition of human urokinase assessed as reduction in release of p-nitroaniline after 10 to 120 mins by Michaelis-Menten equation analysis | Homo sapiens | 4 | ALA3779805 | single protein format | Scientific Literature | |
20. | ALA3783221 | B | Inhibition of human coagulation chymotrypsin assessed as reduction in release of p-nitroaniline after 10 to 120 mins by Michaelis-Menten equation analysis | Homo sapiens | 4 | ALA3779805 | assay format | Scientific Literature |