# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA641402 | F | In vitro efficacy calculated by chlorine current assay on alpha-1-beta-2-gamma-2 (GABA-A) receptor subtype | 52 | assay format | Scientific Literature | |||
2. | ALA652450 | B | Binding affinity against benzodiazepine receptor (BzR) in rat cortical membranes determined by competition experiments with radiolabeled [3H]flunitrazepam (Fnz) | Rattus norvegicus | 53 | cell membrane format | Scientific Literature | ||
3. | ALA678605 | B | In vitro efficacy by [35S]t-butyl-bicyclophosphorothionate (TBPS) binding to the picrotoxin convulsant site on the GABA-A receptor chloride complex. | 51 | protein complex format | Scientific Literature | |||
4. | ALA823757 | F | In vitro efficacy as change in chloride current against GABA-A alpha-3-beta-2-gamma-2 subunit expression | 10 | assay format | Scientific Literature | |||
5. | ALA822834 | F | Ability to antagonize metrazole-induced seizures (clonic and tonic) in mice after intraperitoneal injection | Mus musculus | 46 | organism-based format | Scientific Literature | ||
6. | ALA821971 | F | Compound was tested for Acute electroshock physical dependence activity (drug MA50/V122 MA50); No significant activity | Mus musculus | 3 | organism-based format | Scientific Literature | ||
7. | ALA841482 | F | Antagonism of benzodiazepine traction in mice | Mus musculus | 17 | organism-based format | Scientific Literature | ||
8. | ALA841483 | F | Compound was tested for ethanol potentiation expressed as loss of righting reflex (anesthesia) | Mus musculus | 13 | organism-based format | Scientific Literature | ||
9. | ALA840727 | F | Compound was tested for ethanol potentiation expressed as the loss of traction response (muscle relaxation) | Mus musculus | 13 | organism-based format | Scientific Literature |