| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3782901 | B | Displacement of [3H]SP from human NK1 receptor transfected in CHO cells by liquid scintillation counting method | Homo sapiens | 10 | ALA3779864 | cell-based format | Scientific Literature | |
| 2. | ALA3783006 | B | Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contraction | Cavia porcellus | 11 | ALA3779864 | tissue-based format | Scientific Literature | |
| 3. | ALA3783007 | B | Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contraction | Mus musculus | 11 | ALA3779864 | tissue-based format | Scientific Literature | |
| 4. | ALA3783008 | B | Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane after 2 hrs | Rattus norvegicus | 11 | ALA3779864 | cell membrane format | Scientific Literature | |
| 5. | ALA3783009 | B | Displacement of [3H]DSLET from delta opioid receptor in rat brain membrane after 2 hrs | Rattus norvegicus | 11 | ALA3779864 | cell membrane format | Scientific Literature | |
| 6. | ALA3783010 | B | Antagonist activity against human NK1 receptor expressed in CHO-K1 cells by aequorin luminescence assay based Schild's plot analysis | Homo sapiens | 10 | ALA3779864 | cell-based format | Scientific Literature | |
| 7. | ALA3783012 | F | Antinociceptive activity in naive Wistar rat at 10 nmol, it after 30 mins by tail flick test analysis | Rattus norvegicus | 1 | ALA3779864 | organism-based format | Scientific Literature | |
| 8. | ALA3783015 | F | Antinociceptive activity in Wistar rat model of chronic constriction injury-induced neuropathic pain assessed as reduction in hyperalgesia at 0.8 to 3.5 nmol after 30 mins by cold plate test | Rattus norvegicus | 4 | ALA3779864 | organism-based format | Scientific Literature | |
| 9. | ALA3783016 | F | Antinociceptive activity in Wistar rat model of chronic constriction injury-induced neuropathic pain assessed as reduction in allodynia at 0.8 to 3.5 nmol after 30 mins by von Frey test | Rattus norvegicus | 4 | ALA3779864 | organism-based format | Scientific Literature | |
| 10. | ALA3783017 | F | Potency index, ratio of antinociceptive activity of compound at 8 to 10 nmol, it to antinociceptive activity of morphine at 35 nmol, it in naive Wistar rat after 30 mins | Rattus norvegicus | 3 | ALA3779864 | organism-based format | Scientific Literature | |
| 11. | ALA3783018 | F | Potency index, ratio of antiallodynic effect of compound to antiallodynic effect of morphine in it dosed naive Wistar rat at 0.8 to 3.5 nmol after 30 mins by cold plate test | Rattus norvegicus | 2 | ALA3779864 | organism-based format | Scientific Literature | |
| 12. | ALA3783019 | F | Antinociceptive activity in Wistar rat model of chronic constriction injury-induced neuropathic pain assessed as reduction in allodynia at 3.5 nmol, it QD for 6 consecutive days by von Frey test | Rattus norvegicus | 4 | ALA3779864 | organism-based format | Scientific Literature | |
| 13. | ALA3782301 | F | Antinociceptive activity in Wistar rat model of chronic constriction injury-induced neuropathic pain assessed as reduction in allodynia at 1 nmol, it QD for 6 consecutive days by von Frey test | Rattus norvegicus | 1 | ALA3779864 | organism-based format | Scientific Literature | |
| 14. | ALA3782302 | F | Antinociceptive activity in Wistar rat model of chronic constriction injury-induced neuropathic pain assessed as reduction in hyperalgesia at 1 nmol, it QD for 6 consecutive days by cols plate test | Rattus norvegicus | 1 | ALA3779864 | organism-based format | Scientific Literature | |
| 15. | ALA3782304 | F | Antinociceptive activity in Wistar rat model of chronic constriction injury-induced neuropathic pain assessed as reduction in hyperalgesia at 1 nmol, it QD for 6 consecutive days measured on day-4 and day-5 by cold plate test relative to morphine | Rattus norvegicus | 1 | ALA3779864 | organism-based format | Scientific Literature | |
| 16. | ALA3782305 | F | Antinociceptive activity in Wistar rat model of chronic constriction injury-induced neuropathic pain assessed as reduction in hyperalgesia at 3.5 nmol dosed on day7 after tolerance development with compound13 dosed at 1 nmol, it QD for 6 days by cold plate test | Rattus norvegicus | 2 | ALA3779864 | organism-based format | Scientific Literature | |
| 17. | ALA3782344 | F | Antinociceptive activity in Wistar rat model of chronic constriction injury-induced neuropathic pain assessed as reduction in hyperalgesia at 1 nmol dosed on day7 after tolerance development with morphine dosed at 3.5 nmol, it QD for 6 days by cold plate test | Rattus norvegicus | 1 | ALA3779864 | organism-based format | Scientific Literature | |
| 18. | ALA3782345 | F | Antinociceptive activity in Wistar rat model of chronic constriction injury-induced neuropathic pain assessed as reduction in allodynia at 1 nmol dosed on day7 after tolerance development with morphine dosed at 3.5 nmol, it QD for 6 days by von Frey test | Rattus norvegicus | 1 | ALA3779864 | organism-based format | Scientific Literature |
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