# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3783899 | T | Toxicity in nu/nu mouse xenografted with K562 cells assessed as decrease in body weight at 25 and 50 mg/kg/day, qd administered through oral gavage for 16 days measured every day during compound dosing | Mus musculus | 1 | organism-based format | Scientific Literature | ||
2. | ALA3783900 | F | Induction of apoptosis in human KU812 cells assessed as increase in cleaved PARP level at 100 nM after 24 hrs by immunoblotting method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA3783901 | A | Antiproliferative activity against mouse BA/F3 cells assessed as cell viability after 72 hrs by CellTiter-Glo or CCK-8 assay | Mus musculus | 44 | cell-based format | Scientific Literature | ||
4. | ALA3783902 | B | Inhibition of Tel-ABL (unknown origin) expressed in mouse BA/F3 cells assessed as cell growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay | Homo sapiens | 41 | cell-based format | Scientific Literature | ||
5. | ALA3783994 | F | Antiproliferative activity against human K562 cells assessed as cell viability after 72 hrs by CellTiter-Glo or CCK-8 assay | Homo sapiens | 44 | cell-based format | Scientific Literature | ||
6. | ALA3783995 | B | Inhibition of full length recombinant human ABL1 expressed in Baculovirus expression system | Homo sapiens | 1 | assay format | Scientific Literature | ||
7. | ALA3783996 | B | Inhibition of GST-tagged human DDR1 (440 to 876 residues) expressed in Baculovirus expression system | Homo sapiens | 1 | assay format | Scientific Literature | ||
8. | ALA3783997 | B | Inhibition of recombinant human GST-tagged DDR2 expressed in Baculovirus expression system | Homo sapiens | 1 | assay format | Scientific Literature | ||
9. | ALA3783998 | B | Inhibition of His-tagged recombinant human c-Kit without catalytic domain expressed in mammalian expression system | Homo sapiens | 1 | assay format | Scientific Literature | ||
10. | ALA3783999 | B | Inhibition of full length recombinant GST-tagged human p38-alpha expressed in Escherichia coli | Homo sapiens | 1 | assay format | Scientific Literature | ||
11. | ALA3784000 | B | Inhibition of full length recombinant human C-terminal His-tagged SRC expressed in Baculovirus expression system | Homo sapiens | 1 | assay format | Scientific Literature | ||
12. | ALA3784001 | B | Inhibition of BCR/ABL p210 (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay | Homo sapiens | 44 | cell-based format | Scientific Literature | ||
13. | ALA3784002 | B | Inhibition of TEL-SRC (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
14. | ALA3784003 | B | Inhibition of TEL-DDR1 (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
15. | ALA3784004 | B | Inhibition of TEL-DDR2 (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
16. | ALA3784005 | B | Inhibition of TEL-LCK (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
17. | ALA3784006 | B | Inhibition of TEL-BLK (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
18. | ALA3784007 | B | Inhibition of TEL-HCK (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
19. | ALA3784008 | B | Inhibition of BCR/ABL p210-E255K mutant (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
20. | ALA3784009 | B | Inhibition of BCR/ABL p210-F317L mutant (unknown origin) expressed in mouse BA/F3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo or CCK-8 assay | Homo sapiens | 4 | cell-based format | Scientific Literature |