| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3782657 | B | Inhibition of human His6-tagged BRD4 bromodomain 1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) cells using biotin-H4KAc4 as substrate incubated for 2 hrs by alphascreen assay | Homo sapiens | 81 | ALA3779865 | cell-based format | Scientific Literature | |
| 2. | ALA3782658 | B | Binding affinity to human His6-tagged BRD4 bromodomain 1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) cells at 200 uM incubated for 30 mins by SYPRO orange staining based fluorescence thermal shift assay | Homo sapiens | 81 | ALA3779865 | cell-based format | Scientific Literature | |
| 3. | ALA3782659 | B | Binding affinity to human His6-tagged BRD3 bromodomain 1 (P24 to E144 residues) expressed in Escherichia coli BL21(DE3) cells at 200 uM incubated for 30 mins by SYPRO orange staining based fluorescence thermal shift assay | Homo sapiens | 16 | ALA3779865 | cell-based format | Scientific Literature | |
| 4. | ALA3782660 | B | Binding affinity to human His6-tagged EP300 (A1040 to G1161 residues) expressed in Escherichia coli BL21(DE3) cells at 200 uM incubated for 30 mins by SYPRO orange staining based fluorescence thermal shift assay | Homo sapiens | 16 | ALA3779865 | cell-based format | Scientific Literature | |
| 5. | ALA3782661 | B | Binding affinity to human His6-tagged BRD4 bromodomain 1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) cells by isothermal titration calorimetry | Homo sapiens | 14 | ALA3779865 | cell-based format | Scientific Literature | |
| 6. | ALA3782662 | F | Antiproliferative activity against human MV4-11 cells after 72 hrs by CCK8 assay | Homo sapiens | 14 | ALA3779865 | cell-based format | Scientific Literature | |
| 7. | ALA3782663 | F | Antiproliferative activity against human HL60 cells after 72 hrs by CCK8 assay | Homo sapiens | 14 | ALA3779865 | cell-based format | Scientific Literature | |
| 8. | ALA3782664 | F | Antiproliferative activity against human HT-29 cells after 72 hrs by CCK8 assay | Homo sapiens | 14 | ALA3779865 | cell-based format | Scientific Literature | |
| 9. | ALA3782666 | B | Binding affinity to human His6-tagged BRDT bromodomain 1 (N21 to E137 residues) expressed in Escherichia coli BL21(DE3) cells at 200 uM incubated for 30 mins by SYPRO orange staining based fluorescence thermal shift assay | Homo sapiens | 16 | ALA3779865 | cell-based format | Scientific Literature | |
| 10. | ALA3782667 | B | Binding affinity to human His6-tagged BRD2 bromodomain 1 (K77 to N194 residues) expressed in Escherichia coli BL21(DE3) cells at 200 uM incubated for 30 mins by SYPRO orange staining based fluorescence thermal shift assay | Homo sapiens | 16 | ALA3779865 | cell-based format | Scientific Literature | |
| 11. | ALA3782668 | B | Binding affinity to human His6-tagged CREBBP (R1081 to G1197 residues) expressed in Escherichia coli BL21(DE3) cells at 200 uM incubated for 30 mins by SYPRO orange staining based fluorescence thermal shift assay | Homo sapiens | 16 | ALA3779865 | cell-based format | Scientific Literature | |
| 12. | ALA3782669 | B | Binding affinity to human His6-tagged BRD1 (E556 to A688 residues) expressed in Escherichia coli BL21(DE3) cells at 200 uM incubated for 30 mins by SYPRO orange staining based fluorescence thermal shift assay | Homo sapiens | 16 | ALA3779865 | cell-based format | Scientific Literature | |
| 13. | ALA3782670 | B | Binding affinity to human His6-tagged BRD9 (L14 to Q134 residues) expressed in Escherichia coli BL21(DE3) cells at 200 uM incubated for 30 mins by SYPRO orange staining based fluorescence thermal shift assay | Homo sapiens | 16 | ALA3779865 | cell-based format | Scientific Literature | |
| 14. | ALA3782671 | B | Binding affinity to human His6-tagged PCAF (G715 to D831 residues) expressed in Escherichia coli BL21(DE3) cells at 200 uM incubated for 30 mins by SYPRO orange staining based fluorescence thermal shift assay | Homo sapiens | 16 | ALA3779865 | cell-based format | Scientific Literature | |
| 15. | ALA3782787 | B | Binding affinity to human His6-tagged ASH1L (E2433 to E2564 residues) expressed in Escherichia coli BL21(DE3) cells at 200 uM incubated for 30 mins by SYPRO orange staining based fluorescence thermal shift assay | Homo sapiens | 16 | ALA3779865 | cell-based format | Scientific Literature | |
| 16. | ALA3782788 | B | Binding affinity to human His6-tagged BAZ2B (S1858 to S1972 residues) expressed in Escherichia coli BL21(DE3) cells at 200 uM incubated for 30 mins by SYPRO orange staining based fluorescence thermal shift assay | Homo sapiens | 16 | ALA3779865 | cell-based format | Scientific Literature | |
| 17. | ALA3782789 | B | Binding affinity to human His6-tagged TAF1 bromodomain 1 (R1377 to D1503 residues) expressed in Escherichia coli BL21(DE3) cells at 200 uM incubated for 30 mins by SYPRO orange staining based fluorescence thermal shift assay | Homo sapiens | 16 | ALA3779865 | cell-based format | Scientific Literature | |
| 18. | ALA4012419 | B | Inhibition of human BRD4-BD1 (49 to 170 residues) expressed in Escherichia coli BL21(DE3) using N-C:SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGA-K(Ac)-RHRKVGG-K(biotin) as substrate preincubated for 15 mins followed by substrate addition measured after 5 mins by AlphaScreen assay | Homo sapiens | 53 | ALA4011609 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!