# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3783186 | Binding | Inhibition of HCK (unknown origin) preincubated for 2 hrs followed by FRET peptide addition measured after 1 hr by Z-LYTE assay | Homo sapiens | 30 | ALA3779765 | single protein format | Scientific Literature | |
2. | ALA3783187 | Binding | Inhibition of human recombinant p38 gamma assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addition measured after 1 hr by Z-LYTE assay | Homo sapiens | 30 | ALA3779765 | single protein format | Scientific Literature | |
3. | ALA3783188 | Functional | Antiinflammatory activity in differentiated human U937 cells assessed as inhibition of LPS-induced TNFalpha production preincubated for 2 hrs followed by LPS-stimulation for 4 hrs by sandwich ELISA relative to vehicle-treated control | Homo sapiens | 30 | ALA3779765 | cell-based format | Scientific Literature | |
4. | ALA3783189 | Binding | Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addition measured after 1 hr by Z-LYTE assay | Homo sapiens | 30 | ALA3779765 | single protein format | Scientific Literature | |
5. | ALA3783190 | Functional | Antiinflammatory activity in differentiated human U937 cells assessed as inhibition of LPS-induced of CXCL8 production preincubated for 2 hrs followed by LPS-stimulation for 4 hrs by sandwich ELISA relative to vehicle-treated control | Homo sapiens | 30 | ALA3779765 | cell-based format | Scientific Literature |