# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3783092 | F | Cytotoxicity against human SKOV3 cells | Homo sapiens | 1 | ALA3779870 | cell-based format | Scientific Literature | |
2. | ALA3783094 | A | Metabolic stability in human liver microsomes assessed as compound remaining after 60 mins | Homo sapiens | 2 | ALA3779870 | tissue-based format | Scientific Literature | |
3. | ALA3783095 | A | AUC (0 to t) in Sprague-Dawley rat | Rattus norvegicus | 2 | ALA3779870 | organism-based format | Scientific Literature | |
4. | ALA3783096 | A | AUC (0 to infinity) in Sprague-Dawley rat | Rattus norvegicus | 2 | ALA3779870 | organism-based format | Scientific Literature | |
5. | ALA3783097 | A | Total clearance in Sprague-Dawley rat plasma | Rattus norvegicus | 2 | ALA3779870 | organism-based format | Scientific Literature | |
6. | ALA3783098 | A | Apparent volume of distribution in Sprague-Dawley rat | Rattus norvegicus | 2 | ALA3779870 | organism-based format | Scientific Literature | |
7. | ALA3783099 | A | Drug metabolism in rat liver microsomes assessed as metabolite M1 formation at 10 uM preincubated for 5 mins followed by addition of NADPH measured after 120 mins by HPLC-TIC chromatography | Rattus norvegicus | 1 | ALA3779870 | tissue-based format | Scientific Literature | |
8. | ALA3783100 | A | Drug metabolism in rat liver microsomes assessed as metabolite M2 formation at 10 uM preincubated for 5 mins followed by addition of NADPH measured after 120 mins by HPLC-TIC chromatography | Rattus norvegicus | 1 | ALA3779870 | tissue-based format | Scientific Literature | |
9. | ALA3784105 | A | Drug metabolism in rat liver microsomes assessed as metabolite M3 formation at 10 uM preincubated for 5 mins followed by addition of NADPH measured after 120 mins by HPLC-TIC chromatography | Rattus norvegicus | 1 | ALA3779870 | tissue-based format | Scientific Literature | |
10. | ALA3784106 | A | Drug metabolism in rat liver microsomes assessed as metabolite M4 formation at 10 uM preincubated for 5 mins followed by addition of NADPH measured after 120 mins by HPLC-TIC chromatography | Rattus norvegicus | 1 | ALA3779870 | tissue-based format | Scientific Literature | |
11. | ALA3784224 | A | Drug metabolism in rat liver microsomes assessed as 7-epi-3FDT formation at 10 uM preincubated for 5 mins followed by addition of NADPH measured after 120 mins by HPLC-TIC chromatography | Rattus norvegicus | 1 | ALA3779870 | tissue-based format | Scientific Literature | |
12. | ALA3784227 | A | Drug metabolism in Sprague-Dawley rat plasma assessed as metabolite M4 formation at 40 mg/kg, iv administered as single dose after 4 to 24 hrs by HPLC-TIC chromatography | Rattus norvegicus | 1 | ALA3779870 | organism-based format | Scientific Literature | |
13. | ALA3784228 | A | Drug metabolism in Sprague-Dawley rat plasma assessed as 7-epi-3FDT formation at 40 mg/kg, iv administered as single dose after 4 to 24 hrs by HPLC-TIC chromatography | Rattus norvegicus | 1 | ALA3779870 | organism-based format | Scientific Literature | |
14. | ALA3784229 | A | Drug metabolism in Sprague-Dawley rat urine assessed as metabolite M4 formation at 40 mg/kg, iv administered as single dose after 24 hrs by HPLC-TIC chromatography | Rattus norvegicus | 1 | ALA3779870 | organism-based format | Scientific Literature | |
15. | ALA3784230 | A | Drug metabolism in Sprague-Dawley rat urine assessed as 7-epi-3FDT formation at 40 mg/kg, iv administered as single dose after 24 hrs by HPLC-TIC chromatography | Rattus norvegicus | 1 | ALA3779870 | organism-based format | Scientific Literature | |
16. | ALA3784231 | A | Drug metabolism in Sprague-Dawley rat feces assessed as metabolite M4 formation at 40 mg/kg, iv administered as single dose after 24 hrs by HPLC-TIC chromatography | Rattus norvegicus | 1 | ALA3779870 | organism-based format | Scientific Literature | |
17. | ALA3784232 | A | Drug metabolism in Sprague-Dawley rat feces assessed as 7-epi-3FDT formation at 40 mg/kg, iv administered as single dose after 24 hrs by HPLC-TIC chromatography | Rattus norvegicus | 1 | ALA3779870 | organism-based format | Scientific Literature | |
18. | ALA3784233 | A | Drug metabolism in human liver microsomes assessed as metabolite M1 formation at 10 uM preincubated for 5 mins followed by NADPH measured after 120 mins by HPLC-TIC chromatography | Homo sapiens | 1 | ALA3779870 | tissue-based format | Scientific Literature | |
19. | ALA3784234 | A | Drug metabolism in human liver microsomes assessed as metabolite M2 formation at 10 uM preincubated for 5 mins followed by NADPH measured after 120 mins by HPLC-TIC chromatography | Homo sapiens | 1 | ALA3779870 | tissue-based format | Scientific Literature | |
20. | ALA3784235 | A | Drug metabolism in human liver microsomes assessed as metabolite M3 formation at 10 uM preincubated for 5 mins followed by NADPH measured after 120 mins by HPLC-TIC chromatography | Homo sapiens | 1 | ALA3779870 | tissue-based format | Scientific Literature |