# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3783093 | ADME | Drug level in rat liver microsomes treated with 3FDT at 10 uM preincubated for 5 mins followed by addition of NADPH measured after 120 mins by HPLC-TIC chromatography | Rattus norvegicus | 5 | ALA3779870 | tissue-based format | Scientific Literature | |
2. | ALA3784225 | ADME | Retention time of the compound in rat liver microsomes treated with 10 uM 3FDT by HPLC analysis in presence of NADPH | Rattus norvegicus | 5 | ALA3779870 | tissue-based format | Scientific Literature | |
3. | ALA3782980 | ADME | Drug level in Sprague-Dawley rat plasma treated with 3FDT at 40 mg/kg, iv administered as single dose after 4 to 24 hrs by HPLC-TIC chromatography | Rattus norvegicus | 2 | ALA3779870 | organism-based format | Scientific Literature | |
4. | ALA3782981 | ADME | Drug level in Sprague-Dawley rat urine treated with 3FDT at 40 mg/kg, iv administered as single dose after 24 hrs by HPLC-TIC chromatography | Rattus norvegicus | 2 | ALA3779870 | organism-based format | Scientific Literature | |
5. | ALA3782982 | ADME | Drug level in Sprague-Dawley rat feces treated with 3FDT at 40 mg/kg, iv administered as single dose after 24 hrs by HPLC-TIC chromatography | Rattus norvegicus | 7 | ALA3779870 | organism-based format | Scientific Literature | |
6. | ALA3782983 | ADME | Drug level in human liver microsomes treated with 3FDT at 10 uM preincubated for 5 mins followed by NADPH measured after 120 mins by HPLC-TIC chromatography | Homo sapiens | 5 | ALA3779870 | tissue-based format | Scientific Literature | |
7. | ALA3782986 | ADME | Drug level assessed as recombinant human CYP2E1 mediated compound formation from 3FDT at 10 uM preincubated for 5 mins followed by addition of NADPH measured after 120 mins by HPLC-TIC chromatography | Homo sapiens | 1 | ALA3779870 | single protein format | Scientific Literature |