| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3783933 | Binding | Inhibition of human CYP17A1 expressed in HEK293 cell microsomes using [3H]-pregnenolone as substrate incubated for 45 mins by scintillation proximity assay in presence of NADPH | Homo sapiens | 12 | ALA3779801 | cell-based format | Scientific Literature | |
| 2. | ALA3783934 | ADME | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 12 | ALA3779801 | single protein format | Scientific Literature | |
| 3. | ALA3783935 | ADME | Metabolic stability in human liver microsomes assessed as parent compound remaining at 0.5 uM incubated for 10 mins | Homo sapiens | 12 | ALA3779801 | tissue-based format | Scientific Literature | |
| 4. | ALA3783936 | ADME | Metabolic stability in mouse liver microsomes assessed as parent compound remaining at 0.5 uM incubated for 10 mins | Mus musculus | 12 | ALA3779801 | tissue-based format | Scientific Literature | |
| 5. | ALA3783937 | ADME | Metabolic stability in cynomolgus monkey liver microsomes assessed as parent compound remaining at 0.5 uM incubated for 10 mins | Macaca fascicularis | 12 | ALA3779801 | tissue-based format | Scientific Literature | |
| 6. | ALA3784028 | Binding | Selectivity ratio of human CYP17A1 hydroxylase activity expressed in Escherichia coli using pregnenolone substrate to human CYP17A1 lyase activity expressed in HEK293 cell microsomes using [3H]-hydroxypregnenolone substrate | Homo sapiens | 6 | ALA3779801 | cell-based format | Scientific Literature |
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