# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3784464 | B | Agonist activity at S1P1 receptor (unknown origin) expressed in CHO cells incubated for 2 hrs by HTRF-IP1 assay | Homo sapiens | 6 | ALA3779869 | cell-based format | Scientific Literature | |
2. | ALA3784465 | B | Agonist activity at S1P3 receptor (unknown origin) expressed in CHO cells incubated for 2 hrs by HTRF-IP1 assay | Homo sapiens | 6 | ALA3779869 | cell-based format | Scientific Literature | |
3. | ALA3784467 | A | Drug metabolism in Sprague-Dawley rat blood assessed as formation of 2-amino-2-(2-(4'-(2-(1-hydroxyethyl)oxazol-4-yl)biphenyl-4-yl)ethyl)propane-1,3-diol hydrochloride at 3 mg/kg, po measured at 0.08 to 48 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA3779869 | organism-based format | Scientific Literature | |
4. | ALA3784472 | F | Lymphopenia activity in Sprague-Dawley rat assessed as decrease in lymphocytes in peripheral blood at 3 mg/kg, po after 24 hrs by hematology analyzer | Rattus norvegicus | 4 | ALA3779869 | organism-based format | Scientific Literature | |
5. | ALA4629206 | B | Agonist activity at S1P1 (unknown origin) by HTRF assay | Homo sapiens | 5 | ALA4627363 | single protein format | Scientific Literature | |
6. | ALA4629207 | B | Agonist activity at S1PR3 (unknown origin) by HTRF assay | Homo sapiens | 5 | ALA4627363 | single protein format | Scientific Literature | |
7. | ALA4629209 | A | Drug metabolism in rat blood assessed as (S)-4-(4'-(2-ethyloxazol-4-yl)biphenyl-4-yl)-2-(hydroxymethyl)-2-(1-oxoisoindolin-2-yl)butyl dihydrogen phosphate metabolite formation after 6 hr post dose by HPLC analysis | Rattus norvegicus | 1 | ALA4627363 | tissue-based format | Scientific Literature |