| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3784464 | B | Agonist activity at S1P1 receptor (unknown origin) expressed in CHO cells incubated for 2 hrs by HTRF-IP1 assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 2. | ALA3784465 | B | Agonist activity at S1P3 receptor (unknown origin) expressed in CHO cells incubated for 2 hrs by HTRF-IP1 assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 3. | ALA3784466 | B | Selectivity ratio of EC50 for S1P3 receptor (unknown origin) to EC50 for S1P1 receptor (unknown origin) | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 4. | ALA3784468 | A | Drug metabolism in Sprague-Dawley rat blood assessed as formation of 2-amino-2-(2-(4'-(2-(2-hydroxypropyl)oxazol-4-yl)biphenyl-4-yl)ethyl)propane-1,3-diol hydrochloride at 3 mg/kg, po measured at 0.08 to 48 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA3784472 | F | Lymphopenia activity in Sprague-Dawley rat assessed as decrease in lymphocytes in peripheral blood at 3 mg/kg, po after 24 hrs by hematology analyzer | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 6. | ALA4672286 | A | Prodrug conversion in human blood assessed as SPHK1/SPHK2-mediated compound phosphorylation by measuring intrinsic clearance by LC-MS/MS analysis | Homo sapiens | 4 | tissue-based format | Scientific Literature | ||
| 7. | ALA4672287 | A | Prodrug conversion in human blood assessed as SPHK1/SPHK2-mediated compound phosphorylation by measuring Vmax by LC-MS/MS analysis | Homo sapiens | 4 | tissue-based format | Scientific Literature | ||
| 8. | ALA4672288 | A | Prodrug conversion in human blood assessed as SPHK1/SPHK2-mediated compound phosphorylation by measuring Km by LC-MS/MS analysis | Homo sapiens | 4 | tissue-based format | Scientific Literature | ||
| 9. | ALA4672289 | A | Prodrug conversion in rat blood assessed as SPHK1/SPHK2-mediated compound phosphorylation by measuring Vmax by LC-MS/MS analysis | Rattus norvegicus | 4 | tissue-based format | Scientific Literature | ||
| 10. | ALA4672290 | A | Prodrug conversion in rat blood assessed as SPHK1/SPHK2-mediated compound phosphorylation by measuring Km by LC-MS/MS analysis | Rattus norvegicus | 4 | tissue-based format | Scientific Literature | ||
| 11. | ALA4672291 | A | Prodrug conversion in rat blood assessed as SPHK1/SPHK2-mediated compound phosphorylation by measuring intrinsic clearance by LC-MS/MS analysis | Rattus norvegicus | 4 | tissue-based format | Scientific Literature |
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