# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3784491 | B | Inhibition of human mTOR using ULight-4E-BP1 peptide as substrate after 1 hr by Lance ultra assay | Homo sapiens | 15 | ALA3779897 | single protein format | Scientific Literature | |
2. | ALA3784492 | F | Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay | Homo sapiens | 18 | ALA3779897 | cell-based format | Scientific Literature | |
3. | ALA3784493 | F | Antiproliferative activity against human PC3 cells after 72 hrs by SRB assay | Homo sapiens | 18 | ALA3779897 | cell-based format | Scientific Literature | |
4. | ALA3784494 | F | Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay | Homo sapiens | 12 | ALA3779897 | cell-based format | Scientific Literature | |
5. | ALA3784495 | B | Inhibition of human recombinant PI3Kalpha using PIP2 as substrate after 1 hr by Kinase-Glo luminescent assay | Homo sapiens | 3 | ALA3779897 | single protein format | Scientific Literature | |
6. | ALA3784496 | B | Inhibition of PI3Kbeta (unknown origin) after 1 hr by ADP-Glo luminescent assay | Homo sapiens | 2 | ALA3779897 | single protein format | Scientific Literature | |
7. | ALA3784497 | B | Inhibition of human PI3Kgamma after 1 hr by ADP-Glo luminescent assay | Homo sapiens | 2 | ALA3779897 | single protein format | Scientific Literature | |
8. | ALA3784498 | B | Inhibition of PI3Kdelta (unknown origin) after 1 hr by ADP-Glo luminescent assay | Homo sapiens | 2 | ALA3779897 | single protein format | Scientific Literature | |
9. | ALA3784503 | B | Selectivity ratio, ratio of IC50 for human recombinant PI3Kalpha to IC50 for human mTOR | Homo sapiens | 1 | ALA3779897 | assay format | Scientific Literature | |
10. | ALA3784504 | B | Selectivity ratio, ratio of IC50 for PI3Kbeta (unknown origin) to IC50 for human mTOR | Homo sapiens | 1 | ALA3779897 | assay format | Scientific Literature | |
11. | ALA3784505 | B | Selectivity ratio, ratio of IC50 for human PI3Kgamma to IC50 for human mTOR | Homo sapiens | 1 | ALA3779897 | assay format | Scientific Literature | |
12. | ALA3784506 | B | Selectivity ratio, ratio of IC50 for PI3Kdelta (unknown origin) to IC50 for human mTOR | Homo sapiens | 1 | ALA3779897 | assay format | Scientific Literature | |
13. | ALA3784507 | B | Inhibition of mTORC1 in human MCF7 cells assessed as downregulation of S6 Ser235 phosphorylation at 0.5 uM after 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA3779897 | cell-based format | Scientific Literature | |
14. | ALA3784508 | B | Inhibition of mTORC2 in human MCF7 cells assessed as downregulation of Akt Ser473 phosphorylation at 0.5 uM after 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA3779897 | cell-based format | Scientific Literature | |
15. | ALA3784509 | B | Inhibition of mTORC1 in human MCF7 cells assessed as downregulation of S6 Ser235 phosphorylation at 0.1 uM after 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA3779897 | cell-based format | Scientific Literature | |
16. | ALA3784510 | B | Inhibition of mTORC2 in human MCF7 cells assessed as downregulation of Akt Ser473 phosphorylation at 0.1 uM after 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA3779897 | cell-based format | Scientific Literature |