| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3783739 | B | Inhibition of matripase/hepsin/hepatocyte growth factor activator-mediated HGF activation in human 18Co fibroblasts assessed as scattering of human DU145 cells after 24 hrs by crystal violet staining method | Homo sapiens | 4 | ALA3779883 | cell-based format | Scientific Literature | |
| 2. | ALA3783740 | P | Kinetic solubility of the compound at pH 7.4 | 7 | ALA3779883 | small-molecule physicochemical format | Scientific Literature | ||
| 3. | ALA3783741 | P | Lipophilicity, logD of the compound at pH 7.4 by shake-flask method | 7 | ALA3779883 | small-molecule physicochemical format | Scientific Literature | ||
| 4. | ALA3783742 | A | Half life in human liver microsomes by LC/MS analysis | Homo sapiens | 1 | ALA3779883 | tissue-based format | Scientific Literature | |
| 5. | ALA3783743 | A | Half life in mouse liver microsomes by LC/MS analysis | Mus musculus | 1 | ALA3779883 | tissue-based format | Scientific Literature | |
| 6. | ALA3783744 | A | Permeability of the compound by PAMPA | 1 | ALA3779883 | assay format | Scientific Literature | ||
| 7. | ALA3783745 | A | Half life in mouse at 1 mg/kg, iv | Mus musculus | 1 | ALA3779883 | organism-based format | Scientific Literature | |
| 8. | ALA3783746 | A | Clearance in mouse at 1 mg/kg, iv | Mus musculus | 1 | ALA3779883 | organism-based format | Scientific Literature | |
| 9. | ALA3783747 | A | Volume of distribution in mouse at 1 mg/kg, iv | Mus musculus | 1 | ALA3779883 | organism-based format | Scientific Literature | |
| 10. | ALA3783748 | A | AUC in mouse at 1 mg/kg, iv | Mus musculus | 1 | ALA3779883 | organism-based format | Scientific Literature | |
| 11. | ALA3783749 | A | Cmax in mouse at 5 mg/kg, po | Mus musculus | 1 | ALA3779883 | organism-based format | Scientific Literature | |
| 12. | ALA3783750 | A | AUC in mouse at 5 mg/kg, po | Mus musculus | 1 | ALA3779883 | organism-based format | Scientific Literature | |
| 13. | ALA3783751 | A | Oral bioavailability in mouse at 5 mg/kg | Mus musculus | 1 | ALA3779883 | organism-based format | Scientific Literature | |
| 14. | ALA3782550 | B | Inhibition of human recombinant matripase catalytic domain using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | Homo sapiens | 19 | ALA3779883 | single protein format | Scientific Literature | |
| 15. | ALA3782551 | B | Inhibition of human recombinant hepsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | Homo sapiens | 19 | ALA3779883 | single protein format | Scientific Literature | |
| 16. | ALA3782552 | B | Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | Homo sapiens | 19 | ALA3779883 | cell-based format | Scientific Literature | |
| 17. | ALA3782553 | B | Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | Homo sapiens | 19 | ALA3779883 | protein format | Scientific Literature | |
| 18. | ALA3782596 | B | Inhibition of human recombinant thrombin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | Homo sapiens | 19 | ALA3779883 | single protein format | Scientific Literature | |
| 19. | ALA3782597 | B | Inhibition of human recombinant factor 10a using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | Homo sapiens | 19 | ALA3779883 | single protein format | Scientific Literature | |
| 20. | ALA4374436 | B | Inhibition of recombinant thrombin (unknown origin) using D-Phe-Pip-Arg-pNA as substrate preincubated for 30 mins followed by substrate addition by chromogenic assay | Homo sapiens | 18 | ALA4373666 | single protein format | Scientific Literature |
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