| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3791373 | B | Agonist activity at rat TRPM8 expressed in HEK293 cells assessed as current density at +80 mV holding potential by whole cell patch-clamp assay | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA3791376 | B | Agonist activity at mouse TRPM8 expressed in HEK293 cells assessed as increase in calcium flux at 0.5 uM after 60 mins by Fluo-4 NW dye based fluorometric assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA3791379 | B | Agonist activity at mouse TRPM8 expressed in HEK293 cells assessed as increase in calcium flux at 50 uM after 60 mins by Fluo-4 NW dye based fluorometric assay relative to menthol | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA3791380 | B | Antagonist activity at mouse TRPV1 stably expressed in human SH-SY5Y cells assessed as inhibition of capsaicin mediated calcium flux at 50 uM preincubated for 60 mins followed by capsaicin addition by Fluo-4 NW dye based fluorometric assay in presence of ruthenium dye | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA3791383 | B | Antagonist activity at mouse TRPA1 natively expressed in human IMR90 cells assessed as inhibition of AITC mediated calcium flux at 50 uM preincubated for 60 mins followed by AITC addition by Fluo-4 NW dye based fluorometric assay in presence of ruthenium dye | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3791384 | B | Agonist activity at rat TRPM8 expressed in HEK293 cells assessed as increase in current amplitude at +80 mV holding potential by whole cell patch-clamp assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA3791387 | B | Agonist activity at rat TRPM8 expressed in HEK293 cells assessed as appearance of large outwardly rectifying currents at 100 uM at +80 mV holding potential by whole cell patch-clamp assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4400742 | F | Antibiofilm activity against Candida albicans ATCC 10231 assessed as inhibition of mature biofilm formation by XTT reduction assay | Candida albicans | 24 | organism-based format | Scientific Literature | ||
| 9. | ALA4400743 | F | Antibiofilm activity against Candida albicans ATCC 10231 assessed as inhibition of biofilm formation by XTT reduction assay | Candida albicans | 24 | organism-based format | Scientific Literature | ||
| 10. | ALA4400744 | A | Antifungal activity against planktonic form of Candida albicans ATCC 10231 by broth microdilution method | Candida albicans | 24 | organism-based format | Scientific Literature | ||
| 11. | ALA4400745 | F | Antibiofilm activity against Candida albicans PMC 1042 assessed as inhibition of mature biofilm formation by XTT reduction assay | Candida albicans | 7 | organism-based format | Scientific Literature | ||
| 12. | ALA4400746 | F | Antibiofilm activity against Candida albicans PMC 1042 assessed as inhibition of biofilm formation by XTT reduction assay | Candida albicans | 7 | organism-based format | Scientific Literature | ||
| 13. | ALA4400747 | A | Antifungal activity against planktonic form of Candida albicans PMC 1042 by broth microdilution method | Candida albicans | 7 | organism-based format | Scientific Literature | ||
| 14. | ALA4400748 | F | Antibiofilm activity against Candida albicans PMC 1082 assessed as inhibition of mature biofilm formation by XTT reduction assay | Candida albicans | 7 | organism-based format | Scientific Literature | ||
| 15. | ALA4400749 | F | Antibiofilm activity against Candida albicans PMC 1082 assessed as inhibition of biofilm formation by XTT reduction assay | Candida albicans | 7 | organism-based format | Scientific Literature | ||
| 16. | ALA4400750 | A | Antifungal activity against planktonic form of Candida albicans PMC 1082 by broth microdilution method | Candida albicans | 7 | organism-based format | Scientific Literature | ||
| 17. | ALA4400751 | F | Antibiofilm activity against Candida albicans ATCC 10261 assessed as inhibition of mature biofilm formation by XTT reduction assay | Candida albicans | 7 | organism-based format | Scientific Literature | ||
| 18. | ALA4400752 | F | Antibiofilm activity against Candida albicans ATCC 10261 assessed as inhibition of biofilm formation by XTT reduction assay | Candida albicans | 7 | organism-based format | Scientific Literature | ||
| 19. | ALA4400753 | A | Antifungal activity against planktonic form of Candida albicans ATCC 10261 by broth microdilution method | Candida albicans | 7 | organism-based format | Scientific Literature | ||
| 20. | ALA4400754 | A | Toxicity in Galleria mellonella larvae assessed as larval survival at 500 ug/ml after 24 hrs relative to control | Galleria mellonella | 7 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!