| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3789139 | B | Displacement of [3H]-N-Methyl-Lysergic acid diethylamide from human 5-HT6 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysis | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 2. | ALA3789140 | F | Antagonist activity at human recombinant 5-HT6 receptor expressed in CHO cells assessed as inhibition of agonist induced intracellular calcium levels by aequorin assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 3. | ALA3789141 | A | Permeability across pig LLC-PK1 cells expressing MDR assessed as membrane passage at 1 ug/ml after 3 hrs by LC/MS analysis | Sus scrofa | 26 | cell-based format | Scientific Literature | ||
| 4. | ALA3789142 | A | Permeability across pig LLC-PK1 cells expressing MDR assessed as ratio of bottom to top transport over top to bottom transport at 1 ug/ml after 3 hrs by LC/MS analysis | Sus scrofa | 26 | cell-based format | Scientific Literature | ||
| 5. | ALA3789143 | A | Intrinsic clearance in Sprague Dawley rat hepatocytes after 10 to 60 mins measured per 10'6 cells by HPLC-MS analysis | Rattus norvegicus | 18 | cell-based format | Scientific Literature | ||
| 6. | ALA3789144 | A | Intrinsic clearance in human hepatocytes after 10 to 60 mins measured per 10'6 cells by HPLC-MS analysis | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 7. | ALA3789145 | B | Inhibition of human ERG | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3789146 | B | Binding affinity to dopamine receptor (unknown origin) | Homo sapiens | 1 | protein format | Scientific Literature | ||
| 9. | ALA3789147 | B | Binding affinity to Cannabinoid receptor (unknown origin) | Homo sapiens | 1 | protein format | Scientific Literature | ||
| 10. | ALA3789148 | B | Binding affinity to Muscarinic receptor (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA3789149 | B | Binding affinity to alpha adrenergic receptor (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA3789150 | P | Lipophilicity, log D of the compound at pH 7 | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 13. | ALA3789151 | A | Tmax in rat plasma at 10 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA3789152 | A | Tmax in rat CNS at 10 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA3789153 | A | Clearance in rat at 10 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA3789154 | A | Oral bioavailability in rat at 10 mg/kg | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 17. | ALA3789155 | A | Ratio of drug uptake in rat CNS to plasma at 10 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA3789156 | A | Fraction unbound in rat brain at 10 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA3789157 | F | Inhibition of cognitive impairment in po dosed rat administered 0.5 hrs before testing | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA3789158 | A | Cmax in rat plasma at 20 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature |
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