# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3789139 | B | Displacement of [3H]-N-Methyl-Lysergic acid diethylamide from human 5-HT6 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysis | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
2. | ALA3789140 | F | Antagonist activity at human recombinant 5-HT6 receptor expressed in CHO cells assessed as inhibition of agonist induced intracellular calcium levels by aequorin assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
3. | ALA3789141 | A | Permeability across pig LLC-PK1 cells expressing MDR assessed as membrane passage at 1 ug/ml after 3 hrs by LC/MS analysis | Sus scrofa | 26 | cell-based format | Scientific Literature | ||
4. | ALA3789142 | A | Permeability across pig LLC-PK1 cells expressing MDR assessed as ratio of bottom to top transport over top to bottom transport at 1 ug/ml after 3 hrs by LC/MS analysis | Sus scrofa | 26 | cell-based format | Scientific Literature | ||
5. | ALA3789143 | A | Intrinsic clearance in Sprague Dawley rat hepatocytes after 10 to 60 mins measured per 10'6 cells by HPLC-MS analysis | Rattus norvegicus | 18 | cell-based format | Scientific Literature | ||
6. | ALA3789144 | A | Intrinsic clearance in human hepatocytes after 10 to 60 mins measured per 10'6 cells by HPLC-MS analysis | Homo sapiens | 18 | cell-based format | Scientific Literature |