# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3791390 | B | Binding affinity to recombinant human IL-17A assessed as protection from deuterium uptake at 90 to 101 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
2. | ALA3791391 | B | Binding affinity to recombinant human IL-17A assessed as protection from deuterium uptake at 92 to 99 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
3. | ALA3791633 | B | Binding affinity to recombinant human IL-17A assessed as protection from deuterium uptake at 92 to 101 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
4. | ALA3791634 | B | Binding affinity to recombinant human IL-17A assessed as protection from deuterium uptake at 99 to 103 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
5. | ALA3788850 | B | Binding affinity to recombinant human IL-17A assessed as protection from deuterium uptake at 58 to 71 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
6. | ALA3788851 | B | Binding affinity to recombinant human IL-17A assessed as protection from deuterium uptake at 58 to 72 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
7. | ALA3788852 | B | Binding affinity to recombinant human IL-17A assessed as increase in deuterium uptake at 103 to 114 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
8. | ALA3788853 | B | Binding affinity to recombinant human IL-17A assessed as increase in deuterium uptake at 104 to 116 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
9. | ALA3788854 | B | Binding affinity to recombinant human IL-17A assessed as increase in deuterium uptake at 100 to 116 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
10. | ALA3788855 | B | Binding affinity to recombinant human IL-17A assessed as increase in deuterium uptake at 102 to 116 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
11. | ALA3789082 | B | Binding affinity to recombinant human IL-17A assessed as increase in deuterium uptake at 102 to 120 residues at 10 uM after 10 to 3600 secs by HDX-MS | Homo sapiens | 3 | ALA3785014 | single protein format | Scientific Literature | |
12. | ALA5034281 | B | Inhibition of IL-17A (unknown origin) by ELISA II | Homo sapiens | 2 | ALA5033997 | single protein format | Scientific Literature | |
13. | ALA5034282 | B | Binding affinity to IL-17A (unknown origin) measured by SPR assay | Homo sapiens | 6 | ALA5033997 | single protein format | Scientific Literature | |
14. | ALA5136701 | F | Inhibition of IL-8 release in non-glycosylated IL-17A/TNFalpha-stimulated human HEKa incubated for 72 hrs under serum free medium by AlphaLISA | Homo sapiens | 23 | ALA5131568 | cell-based format | Scientific Literature | |
15. | ALA5136702 | F | Inhibition of IL-8 release in glycosylated IL-17A/TNFalpha-stimulated human HEKa incubated for 72 hrs under serum free medium by AlphaLISA | Homo sapiens | 9 | ALA5131568 | cell-based format | Scientific Literature | |
16. | ALA5136703 | A | Metabolic stability in human liver microsomes assessed as apparent clearance at 0.5 uM measured upto 40 mins in presence of NADPH by LCMS/MS analysis | Homo sapiens | 23 | ALA5131568 | microsome format | Scientific Literature |