# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3789590 | B | Antagonist activity at human TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells assessed as inhibition of AITC-induced Ca2+ influx preincubated for 2 mins followed by AITC addition measured for 2 mins by Fluo-4 dye based FLIPR assay | Homo sapiens | 34 | ALA3784976 | cell-based format | Scientific Literature | |
2. | ALA3789591 | B | Antagonist activity at rat TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells assessed as inhibition of AITC-induced Ca2+ influx preincubated for 2 mins followed by AITC addition measured for 2 mins by Fluo-4 dye based FLIPR assay | Rattus norvegicus | 34 | ALA3784976 | cell-based format | Scientific Literature | |
3. | ALA3789592 | A | Apparent intrinsic clearance in rat liver microsomes | Rattus norvegicus | 34 | ALA3784976 | tissue-based format | Scientific Literature | |
4. | ALA3789593 | A | Apparent intrinsic clearance in human liver microsomes | Homo sapiens | 34 | ALA3784976 | tissue-based format | Scientific Literature | |
5. | ALA3791635 | B | Antagonist activity at rat TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells assessed as inhibition of AITC-induced 45Ca2+ uptake preincubated for 1 min followed by AITC addition measured after 12 mins | Rattus norvegicus | 7 | ALA3784976 | cell-based format | Scientific Literature | |
6. | ALA3791636 | B | Antagonist activity at human TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells assessed as inhibition of AITC-induced 45Ca2+ uptake preincubated for 1 min followed by AITC addition measured after 12 mins | Homo sapiens | 7 | ALA3784976 | cell-based format | Scientific Literature | |
7. | ALA3791637 | B | Agonist activity at rat TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells by 45Ca2+ uptake assay | Rattus norvegicus | 7 | ALA3784976 | cell-based format | Scientific Literature | |
8. | ALA3791638 | B | Agonist activity at human TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells by 45Ca2+ uptake assay | Homo sapiens | 7 | ALA3784976 | cell-based format | Scientific Literature | |
9. | ALA3789645 | A | Drug level in human liver microsomes treated with 3-((3-(4-Chlorophenethyl)-1,2,4-oxadiazol-5-yl)methyl)pyrido[2,3-d]pyrimidin-4(3H)-one | Homo sapiens | 1 | ALA3784976 | tissue-based format | Scientific Literature | |
10. | ALA3789646 | A | Drug level in rat liver microsomes treated with 3-((3-(4-Chlorophenethyl)-1,2,4-oxadiazol-5-yl)methyl)pyrido[2,3-d]pyrimidin-4(3H)-one | Rattus norvegicus | 1 | ALA3784976 | tissue-based format | Scientific Literature |