| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3789206 | B | Inhibition of recombinant human C-terminal FLAG-tagged KDM2B (1 to 650 residues) expressed in baculovirus infected sf9 cells using biotin-H3K36me2 as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by AlphaLisa assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA3789208 | B | Inhibition of recombinant KDM3B (842 to 1761 residues) (unknown origin) expressed in baculovirus infected sf9 cells using biotin-H3K9me as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by AlphaLisa assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA3789209 | B | Inhibition of recombinant human N-terminal His-tagged KDM4A (1 to 350 residues) expressed in Escherichia coli using methylated biotin-H3K9 substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by AlphaLisa assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 4. | ALA3789210 | B | Inhibition of human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotinylated histone H3 as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by AlphaLisa assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA3789211 | B | Inhibition of KDM4C (1 to 349 residues) (unknown origin) expressed in Escherichia coli using biotinylated histone H3 as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by AlphaLisa assay | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 6. | ALA3789212 | B | Inhibition of KDM5B (1 to 809 residues) (unknown origin) expressed in Escherichia coli using biotin-H3K4me3 as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by AlphaLisa assay | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 7. | ALA3789213 | B | Inhibition of recombinant human N-terminal FLAG-tagged KDM5C (2 to 1560 residues) expressed in baculovirus infected sf9 cells using biotin-H3K4me3 as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by AlphaLisa assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA3789214 | B | Inhibition of KDM6A (919 to 1401 residues) (unknown origin) expressed in Escherichia coli using biotinylated histone H3 as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by AlphaLisa assay | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 9. | ALA3789215 | B | Inhibition of human C-terminal FLAG-tagged KDM6B (1043 residues) expressed in baculovirus infected sf9 cells using H3K27me3 as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by AlphaLisa assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA3789441 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 120 hrs by ATPlite assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA3789447 | B | Inhibition of KDM5B in human U2OS cells assessed as reduction in demethylation of H3K4me3 after 20 hrs by Hoechst 33342 staining based immunofluorescence assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA3789448 | B | Inhibition of KDM5C in human U2OS cells assessed as reduction in demethylation of H3K4me3 after 20 hrs by Hoechst 33342 staining based immunofluorescence assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA5231380 | B | Inhibition of KDM5B (unknown origin) | Homo sapiens | 29 | single protein format | Scientific Literature | ||
| 14. | ALA5231383 | B | Inhibition of KDM6B (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 15. | ALA5237416 | B | Inhibition of N-terminal his6-tagged human KDM5B (1 to 769 residues) expressed in sf9 insect cells incubated for 20 mins by Alphascreen assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 16. | ALA5237418 | B | Inhibition of N-terminal his6-tagged human KDM5A (1 to 797 residues) expressed in sf9 insect cells incubated for 20 mins by Alphascreen assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 17. | ALA5237419 | F | Antiproliferative activity against human MM1.S cells assessed as reduction in cell viability | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 18. | ALA5237426 | B | Inhibition of N-terminal his6-tagged human KDM5C (1 to 839 residues) expressed in sf9 insect cells incubated for 20 mins by Alphascreen assay | Homo sapiens | 2 | cell-based format | Scientific Literature |
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