# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3787812 | B | Inhibition of recombinant human PTP-1B expressed in Escherichia coli TB1 at 50 uM using p-nitrophenyl phosphate as substrate | Homo sapiens | 5 | ALA3784954 | assay format | Scientific Literature | |
2. | ALA3787813 | B | Inhibition of recombinant human PTP-1B expressed in Escherichia coli TB1 using p-nitrophenyl phosphate as substrate | Homo sapiens | 3 | ALA3784954 | assay format | Scientific Literature | |
3. | ALA3787814 | B | Inhibition of recombinant human TC-PTP expressed in Escherichia coli TB1 | Homo sapiens | 2 | ALA3784954 | assay format | Scientific Literature | |
4. | ALA3787815 | B | Inhibition of recombinant human LMW-PTP isoform 1 expressed in Escherichia coli TB1 | Homo sapiens | 2 | ALA3784954 | assay format | Scientific Literature | |
5. | ALA3787816 | B | Inhibition of recombinant human LMW-PTP isoform 2 expressed in Escherichia coli TB1 | Homo sapiens | 2 | ALA3784954 | assay format | Scientific Literature | |
6. | ALA3787817 | B | Reversible inhibition of recombinant human PTP-1B expressed in Escherichia coli TB1 at 10 times IC50 using p-nitrophenyl phosphate as substrate preincubated for 90 mins followed by 400 fold dilution | Homo sapiens | 1 | ALA3784954 | assay format | Scientific Literature | |
7. | ALA3787821 | B | Competitive inhibition of recombinant human PTP-1B expressed in Escherichia coli TB1 using p-nitrophenyl phosphate as substrate by Lineweaver-Burk plot analysis | Homo sapiens | 1 | ALA3784954 | assay format | Scientific Literature | |
8. | ALA3787822 | F | Antidiabetic activity in non insulin dependent streptozotocin/nicotinamide-induced diabetic Wistar rat model assessed as decrease in blood glucose levels at 50 mg/kg, ig administered as single dose measured after 7 hrs by glucometer | Rattus norvegicus | 1 | ALA3784954 | organism-based format | Scientific Literature | |
9. | ALA3787823 | F | Antidiabetic activity in non insulin dependent streptozotocin/nicotinamide-induced diabetic Wistar rat model assessed as decrease in blood glucose levels at 50 mg/kg, ig administered as single dose measured after 3 hrs by glucometer | Rattus norvegicus | 1 | ALA3784954 | organism-based format | Scientific Literature |