# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3788932 | B | Inhibition of recombinant human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected sf9 cells using biotin-H3K4me3 substrate incubated for 30 mins by TR-FRET assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
2. | ALA3788933 | B | Inhibition of recombinant human N-terminal His-FLAG-tagged KDM5B (2 to 751 residues) expressed in baculovirus infected sf9 cells using biotin-H3K4me3 substrate incubated for 30 mins by TR-FRET assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
3. | ALA3788934 | B | Inhibition of recombinant human N-terminal GST-tagged KDM4C (2 to 372 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 substrate incubated for 30 mins by TR-FRET assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
4. | ALA3788935 | B | Inhibition of recombinant human N-terminal His-tagged KDM4A (1 to 350 residues) expressed in Escherichia coli using biotin-H3K9me3 substrate incubated for 30 mins by TR-FRET assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
5. | ALA3788936 | B | Inhibition of recombinant human C-terminal FLAG-tagged KDM2B (1 to 650 residues) expressed in baculovirus infected sf9 cells using biotin-H3K36me2 substrate incubated for 30 mins by alphascreen assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA3788937 | B | Inhibition of KDM5A in human ZR-75-1 cells assessed as reduction in H3K4me3 demethylation incubated for 72 hrs by fluorometric immunoassay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
7. | ALA3788938 | B | Inhibition of KDM5B in human ZR-75-1 cells assessed as reduction in H3K4me3 demethylation incubated for 72 hrs by fluorometric immunoassay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
8. | ALA4257281 | B | Inhibition of recombinant human N-terminal His-FLAG tagged JARID1B (2 to 751 residues) expressed in baculovirus infected sf9 cells using H3K4me3-biotin peptide as substrate after 30 mins in presence of alpha-ketoglutaric acid by LANCE TR-FRET assay | Homo sapiens | 122 | cell-based format | Patent Bioactivity Data | ||
9. | ALA4257282 | B | Inhibition of recombinant human C-terminal FLAG-tagged JARID1A (1 to 1090 residues) expressed in baculovirus infected sf9 cells using H3K4me3-biotin peptide as substrate after 30 mins in presence of alpha-ketoglutaric acid by LANCE TR-FRET assay | Homo sapiens | 120 | cell-based format | Patent Bioactivity Data | ||
10. | ALA4257283 | B | Inhibition of recombinant human N-terminal GST-tagged JMJD2C (2 to 372 residues) expressed in baculovirus infected sf9 cells using H3K9me3-biotin peptide as substrate after 30 mins in presence of alpha-ketoglutaric acid by LANCE TR-FRET assay | Homo sapiens | 163 | cell-based format | Patent Bioactivity Data | ||
11. | ALA4257284 | B | Inhibition of recombinant human N-terminal His-tagged JMJD2A (1 to 350 residues) expressed in Escherichia coli using H3K9me3-biotin peptide as substrate after 30 mins in presence of alpha-ketoglutaric acid by LANCE TR-FRET assay | Homo sapiens | 49 | assay format | Patent Bioactivity Data | ||
12. | ALA4257285 | B | Inhibition of recombinant human C-terminal FLAG-tagged FBXL10 (1 to 650 residues) expressed in baculovirus infected sf9 cells using H3K36me2-biotin peptide as substrate after 30 mins in presence of alpha-ketoglutaric acid by AlphaScreen assay | Homo sapiens | 150 | cell-based format | Patent Bioactivity Data | ||
13. | ALA4257286 | B | Inhibition of KDM5A/KDM5B in human ZR-75-1 cells assessed as increase in H3K4me3 level after 72 hrs by fluorometric immunoblot analysis | Homo sapiens | 34 | cell-based format | Patent Bioactivity Data |