| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3789421 | B | Displacement of FITC-Bak-BH3 peptide probe from N-terminal His-tagged human Mcl-1 (172 to 327 residues) expressed in Escherichia coli BL21(DE3) after 1.5 hrs by FPA based competition assay | Homo sapiens | 64 | ALA3785006 | assay format | Scientific Literature | |
| 2. | ALA3789422 | B | Displacement of FITC-Bak-BH3 peptide probe from N-terminal His-tagged human Mcl-1 (172 to 327 residues) expressed in Escherichia coli BL21(DE3) after 1.5 hrs in presence of 1% FBS by FPA based competition assay | Homo sapiens | 20 | ALA3785006 | assay format | Scientific Literature | |
| 3. | ALA3789423 | B | Displacement of mixture of 4- and 5-(N-(7-(1-(2-((6-(3-carboxy-4-(6-hydroxy-3-oxo-3Hxanthen-9-yl)benzamido)hexyl)amino)-2-oxoethyl)-3,5-dimethyl-1H-pyrazol-4-yl)-6-chloro-3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-1H-indole-2-carbonyl)sulfamoyl)furan-2-carboxylic acid from N-terminal His-tagged human Mcl-1 (172 to 327 residues) expressed in Escherichia coli BL21(DE3) after 1.5 hrs by FPA assay | Homo sapiens | 22 | ALA3785006 | assay format | Scientific Literature | |
| 4. | ALA3789424 | A | Permeability of compound by PAMPA assay | 7 | ALA3785006 | assay format | Scientific Literature | ||
| 5. | ALA3789425 | A | Protein binding in fetal bovine serum | Bos taurus | 5 | ALA3785006 | assay format | Scientific Literature | |
| 6. | ALA3789426 | B | Binding affinity to Bcl-xL (unknown origin) after 1.5 hrs by FPA assay | Homo sapiens | 13 | ALA3785006 | single protein format | Scientific Literature | |
| 7. | ALA3789427 | B | Selectivity ratio of Ki for Bcl-xL (unknown origin) to ratio of Ki for N-terminal His-tagged human Mcl-1 (172 to 327 residues) expressed in Escherichia coli BL21(DE3) | Homo sapiens | 13 | ALA3785006 | assay format | Scientific Literature |
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