# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3789901 | F | Positive allosteric modulatory activity at human mGlu1 receptor expressed in wild type T-Rex293 cells assessed as increase in glutamate-induced calcium mobilization pre-incubated for 2.5 mins before glutamate stimulation for 1 min | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
2. | ALA3789902 | F | Positive allosteric modulatory activity at human mGlu1 receptor expressed in wild type T-Rex293 cells assessed as increase in glutamate-induced calcium mobilization pre-incubated for 2.5 mins before glutamate stimulation for 1 min relative to glutamate alone | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
3. | ALA3789903 | A | Intrinsic clearance in human | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
4. | ALA3789904 | A | Intrinsic clearance in rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
5. | ALA3789905 | A | Stability in rat plasma | Rattus norvegicus | 2 | cell-free format | Scientific Literature | ||
6. | ALA3789906 | A | Stability in human plasma | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
7. | ALA3790236 | A | Inhibition of CYP34A (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
8. | ALA3790237 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
9. | ALA3790238 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
10. | ALA3790239 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature |