# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3790647 | Functional | Antiviral activity against HIV2 ROD infected in human MT4 cells assessed as cell viability after 4 days by MTT assay | Human immunodeficiency virus 2 | 21 | ALA3784991 | organism-based format | Scientific Literature | |
2. | ALA3790648 | Toxicity | Selectivity index, ratio of CC50 for mock infected human MT4 cells to EC50 for HIV2 ROD infected in human MT4 cells | 21 | ALA3784991 | cell-based format | Scientific Literature | ||
3. | ALA3788085 | Functional | Antiviral activity against wild type HIV1 3B infected in human MT4 cells assessed as cell viability after 4 days by MTT assay | Human immunodeficiency virus 1 | 25 | ALA3784991 | organism-based format | Scientific Literature | |
4. | ALA3788086 | Functional | Antiviral activity against HIV1 RES056 harboring reverse transcriptase K103N/YI81C double mutant infected in human MT4 cells assessed as cell viability after 4 days by MTT assay | Human immunodeficiency virus 1 | 12 | ALA3784991 | organism-based format | Scientific Literature | |
5. | ALA3788087 | ADME | Cytotoxicity against mock infected human MT4 cells after 4 days by MTT assay | Homo sapiens | 25 | ALA3784991 | cell-based format | Scientific Literature | |
6. | ALA3788088 | Toxicity | Selectivity index, ratio of CC50 for mock infected human MT4 cells to EC50 for HIV1 3B infected in human MT4 cells | 25 | ALA3784991 | cell-based format | Scientific Literature | ||
7. | ALA3788089 | Toxicity | Selectivity index, ratio of CC50 for mock infected human MT4 cells to EC50 for HIV1 RES056 harboring reverse transcriptase K103N/YI81C double mutant infected in human MT4 cells | 11 | ALA3784991 | cell-based format | Scientific Literature | ||
8. | ALA3788090 | Binding | Inhibition of wild type HIV1 Reverse transcriptase assessed as reduction of biotin deoxyuridine triphosphate incorporation into the wild type HIV1 reverse transcriptase after 1 hr by ELISA | Human immunodeficiency virus 1 | 3 | ALA3784991 | single protein format | Scientific Literature | |
9. | ALA3788091 | Functional | Potency index, ratio of nevirapine EC50 to compound EC50 for HIV1 3B infected in human MT4 cells | Human immunodeficiency virus 1 | 1 | ALA3784991 | organism-based format | Scientific Literature |