| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3788408 | F | Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 2. | ALA3788409 | F | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 3. | ALA3788410 | F | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 4. | ALA3788411 | F | Potency index, ratio of 5-fluorouracil IC50 to compound IC50 for human HCT116 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA3788655 | F | Antiproliferative activity against p53 deficient human HCT116 cells after 48 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 6. | ALA3788656 | F | Cell cycle arrest in human HCT116 cells assessed as accumulation at G1 phase at 0.06 uM after 72 hrs by propidium iodide staining based flow cytometry (Rvb = 31.72 +/- 2.21%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3788660 | F | Cell cycle arrest in human HCT116 cells assessed as accumulation at S phase at 0.06 uM after 72 hrs by propidium iodide staining based flow cytometry (Rvb = 40.55 +/- 1.36%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3792061 | F | Cell cycle arrest in human HCT116 cells assessed as accumulation at G2 phase at 0.06 uM after 72 hrs by propidium iodide staining based flow cytometry (Rvb = 27.73 +/- 3.56%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3792065 | B | Inhibition of MDM2/P53 protein interaction in human HCT116 cells at 0.1 to 1 uM after 24 hrs by immunoprecipitation analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA3792067 | T | Toxicity in ip dosed BALB/c mouse by bliss test | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 11. | ALA3792070 | F | Antitumor activity against human HCT116 cells xenografted in ip dosed BALB/c mouse assessed as tumor growth inhibition administered twice weekly for 4 weeks measured 24 hrs post last dose | Homo sapiens | 3 | organism-based format | Scientific Literature | ||
| 12. | ALA3792071 | T | Toxicity in BALB/c mouse assessed as change in body weight at 100 to 200 mg/kg, ip twice weekly for 4 weeks measured 24 hrs post last dose | Mus musculus | 3 | organism-based format | Scientific Literature |
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