# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3788130 | ADME | Drug metabolism in human liver microsomes assessed as glucuronidation at 10 uM after 24 hrs by mass spectrophotometry in presence of NADPH and UDPGA | Homo sapiens | 7 | ALA3784994 | tissue-based format | Scientific Literature | |
2. | ALA3788132 | Binding | Binding affinity to iron(3) assessed as pFe3+ values after 5 mins | 8 | ALA3784994 | assay format | Scientific Literature | ||
3. | ALA3788133 | Physicochemical | Octanol-water partition coefficient, log P of the compound by shake-flask method | 17 | ALA3784994 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA3788134 | Physicochemical | Octanol-water partition coefficient, log P of the compound with iron complex by shake-flask method | 8 | ALA3784994 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4478546 | Binding | Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Escherichia coli BL21 cells using single-stranded 5'-FAM fluorophore/3'-TAMRA quencher)-labeled 17-mer ssDNA-oligomer substrate measured over 45 mins by FRET analysis | Influenza A virus | 71 | ALA4477214 | cell-based format | Scientific Literature | |
6. | ALA4478547 | Binding | Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Escherichia coli BL21 cells at 200 uM using single-stranded 5'-FAM fluorophore/3'-TAMRA quencher)-labeled 17-mer ssDNA-oligomer substrate measured over 45 mins by FRET analysis | Influenza A virus | 71 | ALA4477214 | cell-based format | Scientific Literature | |
7. | ALA4478548 | Binding | Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Echerichia coli BL21 cells at 50 uM using single-stranded 5'-FAM fluorophore/3'-TAMRA quencher)-labeled 17-mer ssDNA-oligomer substrate measured over 45 mins by FRET analysis | Influenza A virus | 71 | ALA4477214 | cell-based format | Scientific Literature |