# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3796125 | B | Inhibition of HDAC4 in human Jurkat E6-1 cells using Lys-TFA as substrate | Homo sapiens | 14 | ALA3792315 | cell-based format | Scientific Literature | |
2. | ALA3796126 | P | Kinetic solubility of the compound | 14 | ALA3792315 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA3796127 | A | Intrinsic clearance in mouse liver microsomes | Mus musculus | 14 | ALA3792315 | tissue-based format | Scientific Literature | |
4. | ALA3796128 | A | Intrinsic clearance in human liver microsomes | Homo sapiens | 14 | ALA3792315 | tissue-based format | Scientific Literature | |
5. | ALA3796129 | A | Apparent permeability across apical to basolateral side in MDCK cells expressing MDR1 | Canis lupus familiaris | 14 | ALA3792315 | cell-based format | Scientific Literature | |
6. | ALA3796130 | A | Effective efflux ratio of apparent permeability in MDCK cells expressing MDR1 | Canis lupus familiaris | 14 | ALA3792315 | cell-based format | Scientific Literature | |
7. | ALA3796505 | B | Binding affinity to HDAC4 catalytic domain (unknown origin) by surface plasmon resonance assay | Homo sapiens | 3 | ALA3792315 | single protein format | Scientific Literature | |
8. | ALA3796506 | B | Binding affinity to HDAC4 catalytic domain (unknown origin) assessed as association rate constant | Homo sapiens | 2 | ALA3792315 | single protein format | Scientific Literature | |
9. | ALA3796507 | B | Binding affinity to HDAC4 catalytic domain (unknown origin) assessed as dissociation rate constant | Homo sapiens | 2 | ALA3792315 | single protein format | Scientific Literature | |
10. | ALA3796508 | B | Inhibition of HDAC4 catalytic domain (unknown origin) using Boc-Lys(TFA)-AMC as substrate | Homo sapiens | 14 | ALA3792315 | single protein format | Scientific Literature | |
11. | ALA3796509 | B | Inhibition of HDAC5 catalytic domain (unknown origin) using Boc-Lys(TFA)-AMC as substrate | Homo sapiens | 2 | ALA3792315 | single protein format | Scientific Literature | |
12. | ALA3796510 | B | Inhibition of HDAC7 catalytic domain (unknown origin) using Boc-Lys(TFA)-AMC as substrate | Homo sapiens | 2 | ALA3792315 | single protein format | Scientific Literature | |
13. | ALA3796511 | B | Inhibition of HDAC9 catalytic domain (unknown origin) using Boc-Lys(TFA)-AMC as substrate | Homo sapiens | 2 | ALA3792315 | single protein format | Scientific Literature | |
14. | ALA3796512 | B | Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate | Homo sapiens | 2 | ALA3792315 | single protein format | Scientific Literature | |
15. | ALA3796513 | B | Inhibition of HDAC1 (unknown origin) using Boc-Lys(Ac)-AMC as substrate | Homo sapiens | 2 | ALA3792315 | single protein format | Scientific Literature | |
16. | ALA3796514 | B | Inhibition of HDAC2 (unknown origin) using Boc-Lys(Ac)-AMC as substrate | Homo sapiens | 2 | ALA3792315 | single protein format | Scientific Literature | |
17. | ALA3796515 | B | Inhibition of HDAC3/NCoR2 (unknown origin) using Boc-Lys(Ac)-AMC as substrate | Homo sapiens | 2 | ALA3792315 | protein complex format | Scientific Literature | |
18. | ALA3796516 | B | Inhibition of HDAC6 (unknown origin) expressed in HEK cells using Boc-Lys(Ac)-AMC as substrate | Homo sapiens | 2 | ALA3792315 | cell-based format | Scientific Literature | |
19. | ALA3796517 | A | Oral bioavailability in C57Bl/6 mouse plasma at 10 mg/kg | Mus musculus | 3 | ALA3792315 | organism-based format | Scientific Literature | |
20. | ALA3796518 | A | Dose normalized AUC in C57Bl/6 mouse plasma at 10 mg/kg, po | Mus musculus | 3 | ALA3792315 | organism-based format | Scientific Literature |