# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3797006 | B | Inhibition of human ROMK expressed in CHO cells by whole-cell voltage clamp method | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
2. | ALA3797007 | B | Inhibition of human ERG by electrophysiology analysis | Homo sapiens | 8 | single protein format | Scientific Literature | ||
3. | ALA3797008 | B | Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by [86Rb+] flux functional assay | Rattus norvegicus | 27 | cell-based format | Scientific Literature | ||
4. | ALA3797009 | B | Displacement of [35S]-MK499 from human ERG expressed in HEK293 cells | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
5. | ALA3795940 | B | Selectivity index, ratio of IC50 for human ERG to IC50 for rat ROMK | 24 | assay format | Scientific Literature | |||
6. | ALA3795941 | B | Selectivity index, ratio of IC50 for human ERG to IC50 for human ROMK by electrophysiology analysis | Homo sapiens | 8 | assay format | Scientific Literature | ||
7. | ALA3795942 | A | Clearance in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
8. | ALA3795944 | A | Dose normalized AUC in Sprague-Dawley rat at 2 mg/kg, po | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
9. | ALA3795945 | A | Half life of compound in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
10. | ALA3795946 | A | Oral bioavailability in Sprague-Dawley rat at 2 mg/kg | Rattus norvegicus | 5 | organism-based format | Scientific Literature |