# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3795791 | B | Inhibition of KDM5A (unknown origin) using substrate peptide/ascorbate/2-OG/ Fe(2) as substrate at 10 uM preincubated for 15 mins followed by addition of substrate peptide/ ascorbate/2-OG/ Fe(2) measured after 1 hr by AlphaLISA method | Homo sapiens | 23 | single protein format | Scientific Literature | ||
2. | ALA4314466 | F | Antileishmanial activity against wild type Leishmania amazonensis IFLA/BR/67/PH8 promastigotes assessed as parasite viability incubated for 72 hrs by MTT assay | Leishmania amazonensis | 16 | organism-based format | Scientific Literature | ||
3. | ALA4314467 | F | Antileishmanial activity against GFP-expressing Leishmania amazonensis MHOM/BR/75/Josefa intracellular amastigotes infected in murine peritoneal macrophages incubated for 72 hrs by spectrofluorimetry analysis | Leishmania amazonensis | 16 | organism-based format | Scientific Literature | ||
4. | ALA4314468 | A | Cytotoxicity against sodium thioglycolate-stimulated BALB/c mouse peritoneal macrophages measured after 72 hrs | Mus musculus | 16 | cell-based format | Scientific Literature | ||
5. | ALA4314469 | T | Selectivity index, ratio of CC50 for BALB/c mouse peritoneal macrophages to IC50 for GFP-expressing Leishmania amazonensis MHOM/BR/75/Josefa intracellular amastigotes infected in murine peritoneal macrophages | 16 | cell-based format | Scientific Literature |